VIII Multidyscyplinarna Konferencja Nauki o Leku

 on-line journal

No.
 Presenting person
 Title
1 Marek Bajda Novel dual target ligands derivatives of isoindoline-1,3-dione as potential treatment for Alzheimer’s disease
2 Krzysztof Bańkowski Physicochemical characterization of sunitinib and its impurities
3 Krzysztof Bańkowski New cyclic dermorphin analogues containing a carbonyl bridge
4 Lilianna Becan New 4,8-dihydroxy-1-oxo-6-phenyl-1,2-dihydro-2,7-naphthyridine-3-carboxylate derivatives with potential anticancer activity
5 Lilianna Becan Synthesis and in vitro anticancer evaluation of the new thiazolo[4,5-d]pyrimidines.
6 Kamil Brożewicz 1-(2-Mercaptobenzenesulfonyl)-3-hydroxyguanidines – synthesis of novel potent in vitro antiproliferatives
7 Anita Bułakowska Anitiviral activity of chalcones
8 Katarzyna Buś-Kwaśnik Comparison of bisoprolol pharmacokinetics after 10 mg oral administration of Bisocard and reference formulation to healthy subjects
9 Ewa Chodurek Effect of valproic acid and cisplatin on the proliferation of tumor cell lines A375 and C32
10 Ewa Chodurek Examination of free radicals in melanins isolated from A-375 cells exposed on valproic acid and cisplatin by EPR spectroscopy
11 Elwira Chrobak Crystal structures of betulin and its derivatives
12 Jarosław Ciekot Methods for methotrexate determination in macromolecular conjugates drug-carrier
13 Marcin Cybulski Efficient preparation of a key intermediate in the exemestane synthesis
14 Katarzyna E. Filip Investigation of unknown impurities in cyclic dermorphin analogue by HPLC-MS
15 Beata Filip-Psurska Vitamin D analogs enhance the activity of imatinib mesylate in human non-small cell lung cancer model
16 Edyta Gilant Validated HPLC method for the determination of temozolomide in human plasma
18 Tomasz Giller Synthesis of potential impurities of loteprednol etabonate and methods for chemical purity determination
19 Katarzyna Gobis Synthesis and tuberculostatic activity of novel 2-(2-cyclohexylethyl)-1H-benzo[d]imidazoles
20 Katarzyna Komor The role of a sugar moiety in new genitein derivatives affecting proliferation and apoptosis of cancer cells
21 Waldemar Goldeman Synthesis and anti-proliferative activity of selected aromatic bis(aminomethylidenebisphosphonic) acids
22 Tomasz M. Goszczyński Anticancer activity of the conjugates:  modified fibrinogen – methotrexate.
23 Marta Grec The immunochemical studies of the glycinated glycoconjugates based on synthetic thioglycosides as mimic factors of bacterial endotoxins using in the polysaccharide vaccines preparation
24 Marta Grec Synthesis of galactothiophosphoesters of uridine and preliminary tests to evaluate their activity against selected glycosyltransferases
25 Arkadiusz R. Gruchlik Polyunsaturated fatty acids inhibit melanoma cell growth in vitro
26 Arkadiusz R. Gruchlik Effect of Gly-Gly-His, Gly-His-Lys and their copper complexes on the TNF-α – dependent IL-6 secretion in normal human dermal fibroblasts
27 Monika K. Grudzień Molecular properties of antifungal agents – Impact on bioavailability – The Biopharmaceutics Classification System
28 Mariusz M. Gruza Preparation of protoaescigenin from escin.
29 Krystyna Gryz Experience of the Office for Registration of Medicinal Products, Medical Devices and Biocidal Products in assessment of quality of medicinal products
30 Przemysław Hahn Enzymatic synthesis of beta-2-deoxy-D-galactopyrano- sides from glycals
31 Grzegorz Huszcza Manufacturing of modified release tablets
32 Michał Jadwiński Glycosyl thiocarbamates in orthogonal synthesis of oligosaccharides
33 Małgorzata Jarończyk On tautomerism of the pyridodiazepines. A DFT study.
34 Magdalena Jezierska-Zięba An improved preparation of 3,5-bis(2-cyanoisopro- pyl)toluene - key intermediate in Anastrozole synthesis
35 Anna Jończyk Application of silica-bonded ovomucoin protein chiral stationary phase for the determination of paroxetine, clinically used psychotropic drug
36 Kamil K. Kamiński Preliminary studies on a new way of nucleic acids extraction using hydrogel microsphere
37 Krzysztof Kamiński Design, synthesis and anticonvulsant activity of new N-Mannich bases derived from 3-phenylpyrrolidine-  2,5-diones
38 Małgorzata Kapral The effect of inositol hexaphosphate on the transcriptional activity of genes encoding metalloproteinases and their tissue inhibitors in colon cancer cellsstimulated with phorbol-12-myristate 13-acetate
39 Małgorzata Kapral Modulation of the expression of genes encoding TGF-β isoforms and their receptors by inositol hexaphosphate in human colon cancer cells
40 Michał Kaza Bioequivalence study of 500 mg cefuroxime film-coated tablets in healthy volunteers
41 Katarzyna Kempińska Interaction of endotoxin and polymyxin B in B16 mouse melanoma model of metatstasis
42 Gabriela Kłaczkow Search for Huntington's disease biomarkers - amino acid profile analysis using HPLC method
43 Szymon Kłossowski Synthesis of marker compounds for detailed explanation the mechanism of anticancer activity of peptidomimetics with β-acyloxymethacrylic fragment
44 Roman Komor Application of different α-1-thioglycosides preparation methods in synthesis of 5-nitro-pyridyl 1-thioglycosides - substrates in construction of conjugates with uridine moiety
45 Roman Komor The biological activity of sugar derivatives based on quinoline scaffold
46 Marek T. Konieczny Synthesis of new class of cytotoxic chalcone derivatives
47 Mirosława Koronkiewicz Proapoptotic effects of new pentabromobenzylisothioureas and CK2 inhibitor in prostate adenocarcinoma cell line
48 Monika Kosińska HPLC method for determination of the enantiomeric purity of a new ω chain aldehyde synthon used in the synthesis of travoprost
49 Konrad Kowalski ESI-MS/MS techniques for structural analysis of boron clusters
50 Wojciech Cybulski Vaccines for swine authorized on Polish market in 2008 and 2009-change of trends after harmonization according to EU pharmaceutical codex
51 Wojciech Cybulski Karl Fisher determination of a residual moisture in veterinary vaccines - practical implementation in market monitoring
52 Hanna Kruszewska Examination of antimicrobial activity of selected non-antibiotic products
53 Elżbieta S. Kublin Examination of optical isomerism - compounds of antihypertensive effects.
54 Ewa Leciejewicz-Ziemecka Actualities of the European Pharmacopoeia in the Polish Pharmacopoeia
55 Grzegorz Lipner An application of accelerator mass spectrometry (AMS) in pediatric clinical studies. Paracetamol, midazolam and spironolactone radiosynthesis and certification.
56 Grzegorz Lipner An improved process for the preparation of 2-amino-N-tert-butyl-2-cyanoamide hydrochlorie.
57 Małgorzata Lisowska Kuźmicz Application of amylose tris(3,5dimethylphenyl- carbamate) chiral stationary phase for the determination of paroxetine, clinically used psychotropic drug
58 Wojciech Łuniewski Assessment of selected synthesis of bosentan towards elimination of known impurities.
59 Marcin Mączyński Searchıng for new ısoxazole derıvatıves wıth potentıal ımmunorestorıng actıvıty
60 Marta Majewska Application of HPLC for studying purity, content and release profile of temozolomide capsules
61 Jadwiga Maniewska The influence of fluphenazine and its newly synthesized derivatives on the properties of liposomal membranes
62 Aleksander P. Mazurek On Substituent Effect in the on the Benzodiazepinone System
63 Magdalena Milczarek Colon cancer treatment with the use of vitamin D analogs and irinotecan 
64 Małgorzata Milczarek Sulforaphane modulates MRP expression and activity in Caco-2 cells
65 Małgorzata Milczarek The combined effect of 5-fluorouracil and sulforaphane in prostate cancer cell line
66 Bożena Modzelewska-Banachiewicz Biological activities of new amidrazone derivative and its copper (II) complex
67 Barbara Kąkol Application of Corona detector for analysis of 4-cyclohexyl-(S)-proline – key intermediate in Fosinopril synthesis
68 Ewelina Czerniec-Michalik HPLC methods for in–process control and chemical purity determination of olopatadine
69 Bożena Modzelewska-Banachiewicz Anti-inflammatory activity of novel hydrazide derivatives
70 Jacek Musijowski Development and validation of a liquid chromatography / single quadrupole mass spectrometry method for the determination of aripiprazole in human plasma
71 Anna Nasulewicz-Goldeman Biological activity of naphthyl-1,5-diamino-bis (methylidenebisphosphonic) acid – a new bisphosphonate
72 Beata Naumczuk Molecular complexes of topo I and topo II inhibitors from camptothecin and flavonoid families with model DNA oligomers. Search from sequence specific binding. Verification of biological assay on atomic coordinates level.
73 Anna Nowicka Synthesis of new 2-aminobenzimidazole derivatives. Reaction of 2-arylideneaminobenzimidazole with selected nitriles containing active methylene group.
74 Jolanta Obniska Synthesis and anticonvulsant activity of new 5-(cyclo)alkyl-5-phenyl-imidazolidine-2,4-diones derivatives with arylpiperazinylpropyl moiety
75 Jolanta Obniska Synthesis, anticonvulsant activity and 5-HT1A/5-HT7 receptors affinity of new 1-[(4-substituted-  piperazin-1-yl)-alkyl]- 3-methyl- 3-(2-methylpropyl)-pyrrolidine- 2,5-diones
76 Kinga Ostrowska Microwave-assisted synthesis and antimicrobial activity of O-alkylamino derivatives of benzofurancarboxylic acids
77 Katarzyna Papaj Comparison of biological activity and stability of selected C-glycosidic and O-glycosidic genistein derivatives
78 Beata Parfiniewicz Impact of celecoxib on soluble intercellular adhesion molecule-1 (sICAM-1) and soluble E-cadherin (sE-cadherin) concentrations in human colon cancer cell line cultures exposed to phytic acid (IP6) and TNF-α (tumor necrosis factor-alpha)
79 Beata Parfiniewicz The influence of TNF-α (tumor necrosis factor - alpha) on concentration of soluble adhesion molecules in cultures of HT-29 cells exposed to inositol hexaphosphate (IP6)
80 Jadwiga Paszkowska Synthesis and evaluation of inhibitory activity of novel C-5 substituted uridine derivatives
81 Edyta B. Pesta-Dynda Comparative permeation studies of tacalcitol through the human skin from brand product versus generic product
82 Edyta Piórkowska Determination of Sunitinib in human plasma using LC/MS
83 Anita Płazińska Y308 is a key residue of the β2-adrenoceptor to distinguish the Gs selective derivatives of fenoterol
84 Mateusz Psurski Naturally occurring hydroxyalkyl isothiocyanates and isothiocyanatoalkyl benzoates - structure-activity and structure-mechanism of action relationship studies.
85 Mateusz Psurski Novel bifunctional synthetic isothiocyanates with high antiproliferative activity
86 Agata Ptaszek-Budniok Tiocarbamates derivatives of p-nitrobenzyl alcohol as donors in the synthesis of glycoconjugates
87 Andrzej Regiec Synthesis and cytotoxic activity of new Pt (II) complexes with nitropyrazoles in aerobic and hypoxic conditions
88 Andrzej Regiec New method of obtaining of 2-cyano- 3-alkoxy- 2-butenoates
89 Anna Rosa Development and validation of the HPLC-UV method for impurities determination in duloxetine hydrochloride
90 Ewa Sawicka Role of estradiol in chromium-induced oxidative stress
91 Ewa Sawicka New form of coenzyme Q10 (PureSorb-QTM40) inhibits free radicals processes caused by cisplatin.
92 Katarzyna Sidoryk 5H-indolo-[2,3-b]quinolines loaded polymeric micelles
93 Agata Siwek Fungal N-myristoyltransferase as potential target for thiosemicarbazide-based compounds
94 Jarosław J. Sławiński Synthesis and antitumor activity of novel 2 alkylthio-N-(4-R-quinazolin-2-yl)benzenesulfonamides
95 Jarosław J. Sławiński Synthesis of novel 4-substituted pyridine-3-sulfonamide derivatives with potential anticancer activity
96 Urszula Śliwińska-Hill Interaction of an potential copper(I) radiopharmaceuticals with human serum albumin
97 Marta K. Sowińska Novel amphiphilic dendrimers as antibacterial and antitumoral agents.
98 Elżbieta U. Stolarczyk Development and validation of GCMS method for the control of ethyl and izopropyl methanesulphonates in pharmaceutical substance in a form of mesilate
99 Piotr Świątek New isothiazolopyridines and their in vitro antibacterial activity
100 Piotr Świątek The interaction of new fluphenazine analogues with lipid membrane
101 Piotr Świerk Synthesis and in vitro screening of antiproliferative activity of C-glycosides, the derivatives of genistein and daidzein in selected cancer cell lines
102 Elżbieta Szacoń New 1-aryl-6-benzyl imidazo[1,2-a][1,3,5]triazines with potential pharmacological activity.
103 Elżbieta Szacoń Synthesis of new 1-(1-arylimidazolin-2-ylo)-3-(4-methoxyphenyl)urea derivatives.
104 Wojciech J. Szczepek Distinguishing between polymorphic forms of linezolid by solid-phase electronic and vibrational circular dichroism
105 Berenika Szczęśniak-Sięga Synthesis of N-substituted benzo-1,2-thiazine 1,1-dioxide derivatives with potential anti-inflammatory activity
106 Berenika Szczęśniak-Sięga New Mannich bases of N-substituted 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones and their biological properties
107 Bożena Szermer-Olearnik Preparation of endotoxin-free bacteriophages from bacterial lysate
108 Marek Wasek Exposure to ionizing radiation of workers in Poland
109 Joanna M. Wawszczyk Phytic acid down-regulates IL-8 secretion from IL-1β stimulated colonic epithelial cells by influencing mitogen-activated protein kinase signaling pathway.
110 Joanna M. Wawszczyk Effect of phytic acid on the expression of IL-6, IL-8 and NFkB in human colonic epithelial cells treated with IL-1β  
111 Katarzyna Wiglusz The transport of active antineoplastic complexes of Pt(II) by human serum albumin.
112 Katarzyna Wiktorska Formation of Caco-2 monolayer - model for the prediction of intestinal drug absorption; method validation.
113 Daniel Wolny Comparison of dissolution profiles of theophylline extended-release dosage forms
114 Daniel Wolny The effects of 300 mT static magnetic field on IL-6 secretion in normal human colon myofibroblasts
115 Piotr Wroczyński Contribution of ALDH1A1 isozyme to detoxification of aldehydes present in food products.
116 Piotr Wroczyński Inactivation of salivary aldehyde dehydrogenase-influence of antioxidant status in saliva collected in the morning and in the afternoon from smokers and no-smokers.
117 Monika Wujec Microbiologically active Mannich bases derived from 1,2,4-triazoles. The effect of C-5 substituent on antibacterial activity.
118 Paweł Zajdel The multiobjective based design, synthesis and evaluation of the arylsulfonamide/amide derivatives of arylxyethyl- and arylthioethyl- piperidines and pyrrolidines as a novel class of potent 5-HT7 receptor antagonists
119 Paweł Zajdel The highly versatile handle for synthesis of secondary amine derivatives with potential CNS activity: The Pipecolic Linker
120 Lucjusz Zaprutko 3-(egzo)-ene-Derivatives of oleanolic acid as perspective compounds with valuable pharmacological activities
121 Lucjusz Zaprutko The new azole connections as potential biologically active agents
122 Aleksandra A. Zdeb  "Eye Drops - requirements for the product and specifics of production"
123 Paulina Zielińska Effects D-tryptophan substitutions on the activity and toxicity of antimicrobial dendrimers
124 Beata Żołnowska Synthesis of a new series of heteroaryl 4-chloro- 2-mercaptophenylsulfonylisothiourea derivatives with potential antitumor activity
125 Jolanta Dyniewicz Development of new multitarget GPCRs ligands (opioid agonist- tachykinin antagonist).
126 Renata Jachowicz Methods of pharmaceutical availability enhancement
127 Edyta Kuśmierz  Structure-activity relationship studies of 1-diphenylacetyl-4-aryl/alkyl thiosemicarbazides.
128 Joanna Matalińska Anticancer properties of hair proteins digestive peptides
129 Katarzyna Koprek Practical advantages of Microflow-UHPLC
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