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dr Wojciech Łuniewski

e-mail:
phone: +48-22-4563898
fax:
web:
interest(s):

Affiliation:

Instytut Farmaceutyczny

address: Rydygiera 8, Warszawa, 01-793, Poland
phone: +48-22-4563900
fax: +48-22-4563838
web: http://www.ifarm.waw.pl

Participant:

V Multidyscyplinarna Konferencja Nauki o Leku

began: 2006-05-15
ended: 2006-05-17
Presented:
V Multidyscyplinarna Konferencja Nauki o Leku
NEW IMPROVED METHOD OF POLYMORPHIC α FORM OF IMATINIB MESYLATE (GLEEVEC®) SYNTHESIS.
V Multidyscyplinarna Konferencja Nauki o Leku
DISUBSTITUTED INDOLO[2,3-b]QUINOLINE DERIVATIVES. THE CYTOTOXIC ACTIVITY IN VITRO AGAINST VARIOUS HUMAN TUMOR CELL LINE.

Participant:

VI Multidyscyplinarna Konferencja Nauki o Leku

began: 2008-05-25
ended: 2008-05-29
Presented:
VI Multidyscyplinarna Konferencja Nauki o Leku
Disubstituted indolo[2,3-b]quinoline derivatives - the cytotoxic activity in vitro against various human tumor cell lines.
VI Multidyscyplinarna Konferencja Nauki o Leku
Mono substituted 5H- and 6H-indolo[2,3-b]quinoline derivatives and their ability to overcome the barrier of drug resistance.
VI Multidyscyplinarna Konferencja Nauki o Leku
Synthesis of selected 14C radiolabelled compounds in recent investigations of new analytical method applied in accelerated drug development (EUMAPP).

Participant:

VII Multidyscyplinarna Konferencja Nauki o Leku

began: 2010-05-09
ended: 2010-05-13
Presented:
VII Multidyscyplinarna Konferencja Nauki o Leku
Opimisation of preparation of TZ-6

Participant:

VIII Multidyscyplinarna Konferencja Nauki o Leku

began: 2012-05-29
ended: 2012-06-02
Presented:
VIII Multidyscyplinarna Konferencja Nauki o Leku
Assessment of selected synthesis of bosentan towards elimination of known impurities.

Participant:

IX Multidyscyplinarna Konferencja Nauki o Leku

began: 2014-05-11
ended: 2014-05-15
Presented:
IX Multidyscyplinarna Konferencja Nauki o Leku
Improved manufacturing process of bosentan monohydrate.

Publications:
  1. Application of the new data processing method for photodiode array detector in the analysis of drug substances
  2. Assessment of selected synthesis of bosentan towards elimination of known impurities.
  3. Development and validation of the GC method for quantitative determination of semi-volatile solvents in pharmaceutical substance Bosentan
  4. Development and validation of the HPLC-UV method for impurities determination in duloxetine hydrochloride
  5. DISUBSTITUTED INDOLO[2,3-b]QUINOLINE DERIVATIVES. THE CYTOTOXIC ACTIVITY IN VITRO AGAINST VARIOUS HUMAN TUMOR CELL LINE.
  6. Disubstituted indolo[2,3-b]quinoline derivatives - the cytotoxic activity in vitro against various human tumor cell lines.
  7. HPLC as a method for analytical control of synthesis and determination of tolterodine (TD-S)
  8. HPLC method as an analitycal control of synthesis and determination of TZ-S
  9. Improved manufacturing process of bosentan monohydrate.
  10. Investigation of unknown impurity of TD-S by HPLC-MS
  11. Mono substituted 5H- and 6H-indolo[2,3-b]quinoline derivatives and their ability to overcome the barrier of drug resistance.
  12. MONO SUBSTITUTED 5H-INDOLO[2,3-B]- QUINOLINE DERIVATIVES AND THEIR ABILITY TO OVERCOME THE BARRIER OF DRUG RESISTANCE.
  13. NEW IMPROVED METHOD OF POLYMORPHIC α FORM OF IMATINIB MESYLATE (GLEEVEC®) SYNTHESIS.
  14. Opimisation of preparation of TZ-6
  15. QUINONES AND HYDROQUINONES SEPARATION AND DETERMINATION BY HPLC CHROMATOGRAPHY
  16. Synthesis of selected 14C radiolabelled compounds in recent investigations of new analytical method applied in accelerated drug development (EUMAPP).
  17. The comparison of the stability indicating  two HPLC methods and their application for the determination of bosentan in coated tablets 
  18. The evaluation of tolterodine tartrate synthesis based on patent EP 0 325 574 B1.



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