VII Multidyscyplinarna Konferencja Nauki o Leku

 on-line journal

Time
 Duration
 Type
 Presenting person
 Title

Invited oral Maciej Wieczorek RNAi - breakthrough technology gives hope for breakthrough therapeutics

May 9th, Sunday

15:00 REGISTRATION - Registration from 15:00 to 22:00 - Hotel Hyrny - Secretariat VII MKNOL
18:00 Supper - From 18:00 to 20:00 - Hyrny Hotel

May 10th, Monday

07:30 Breakfast
09:00 Session I - Osman Achmatowicz, Zbigniew Kałuża - Conference room
09:15 00:30:00 Invited oral Jacek Kuźnicki High throughput calcium screens for identification of drug targets and drug discovery in neurodegenerative diseases 
09:45 00:30:00 Invited oral Karol L. Grela Olefin metathesis as an emerging tool in the synthesis of natural and bioactive compounds
10:15 00:20:00 Oral Zdzisław Chilmonczyk Alkyl-nitroquipazine derivatives as serotonin transporter and 5-HT1A receptor ligands
10:35 00:20:00 Oral Michał Fedoryński An efficient preparation of 3,5-bis(2-cyanoisopropyl) toluene-key intermediate in Anastrozole synthesis
10:55 Coffee break - Hyrny Hotel - Patio and Garden
11:30 Session II - Elżbieta Anuszewska, Wiesław Szeja - Conference room
11:30 00:30:00 Invited oral Andrzej Kutner Synthetic Technologies of Pharmaceutical Substances
12:00 00:20:00 Oral Katarzyna Kulig Design and synthesis of hybrid structures of pyrrolidin-2-one and arylalkylpiperazine as compounds with potential cardiovascular activity*
12:20 00:20:00 Oral Beata Kolesińska Traceless chiral coupling reagent. A new concept for synthesis of optically active products from racemic carboxylic acids.
12:40 00:20:00 Oral Krzysztof Jóźwiak An old drug with new perspectives: How stereochemistry of fenoterol and fenoterol derivatives influences the β-adrenergic binding and the G-protein coupling selectivity.
13:00 00:20:00 Oral Sławomir Milewski N-alkyl derivatives of nystatin with improved selective toxicity
13:20 Dinner - Hyrny Hotel - Canteen
15:20 Session III - Zofia Lipkowska, Andrzej Kutner - Conference room
15:20 00:30:00 Invited oral Tomasz Ciach Particles for controlled drug delivery
15:50 00:20:00 Oral Bartłomiej Furman Cyclic Enaminones as Building Blocks in the Synthesis of Piperidine-Containing Natural Products and Biolo- gically Active Compounds
16:10 00:20:00 Oral Zbigniew J. Kamiński An Approach for Application of Synthetic Peptides as Markers of Atherosclerotic Diseases
16:30 00:20:00 Oral Barbara Malawska Multi-target-directed ligands in design and discovery of potential drugs for Alzheimer’s disease
16:50 Coffee beak - Hyrny Hotel- Patio and Garden
17:20 Poster Session I (Presentation of posters with odd numbers) - Hyrny Hotel
17:20 #1 Poster Elżbieta Anuszewska Modified SDS micelles for amino acid separation by MEKC. Application for amino acid profiling in formulations for parental use.
17:20 #3 Poster Ewa Augustin Antitumor triazoloacridinone C-1305 as a potent FLT3 tyrosine kinase inhibitor in human leukemia MV4;11 cells.
17:20 #5 Poster Anna Bielawska Inhibition of DNA topoisomerases I and II by G3 PAMAM-NH2 dendrimer - modified digoxin and proscillaridin A conjugates in a cell free system
17:20 #7 Poster Joanna M. Biernat The development of a GC method for analysis of resi- dual acetic acid, triethylamine and N,N-dimethylfor- mamide in hydrochloride salts of pharmaceutical substances
17:20 #9 Poster Janusz Boratyński Antitumor activity of carrier-methotrexate conjugates.
17:20 #11 Poster Grażyna Chłoń-Rzepa Tricyclic derivatives of theophylline as potential ligands of CNS
17:20 #13 Poster Ewa Chodurek Evaluation of proliferation and cellular death of A375 cell line in the presence of HDACs inhibitors
17:20 #15 Poster Zbigniew Dąbrowski Research on isolation and identification of cyclolinopeptides from waste products of the flax linseed (Linum usitatissimum L.)
17:20 #17 Poster Anna Długosz Baicalin inhibits free radicals processes caused by chromium and cisplatin.
17:20 #19 Poster Jolanta Dyniewicz Development of dendrimeric somatostatin analogues
17:20 #23 Poster Jerzy Goliński Synthesis of embutramide in mild conditions
17:20 #25 Poster Beata M. Gruber The possible role of HSP60 in synergistic action of anthracyclines and sulindac in HeLa cells
17:20 #27 Poster Arkadiusz R. Gruchlik Influence of troglitazone, sodium butyrate and 5-aminosalicylic acid on the chemokine ENA-78/CXCL5 secretion in the intestinal subepithelial myofibroblasts
17:20 #29 Poster Krystyna Gryz The Pharmacopoeia in preparation and assessment of pharmaceutical, chemical and biological documentation of medicinal products
17:20 #31 Poster Ewa Leciejewicz-Ziemecka The European Pharmacopoeia in the Polish Pharmacopoeia
17:20 #33 Poster Anna Jończyk Direct enantiomeric resolution of tamsulosin, clinically used chiral O-phenylethanolamine derivative with α1-blocking activity
17:20 #35 Poster Barbara Kąkol Improvement of the Phase-Transfer Catalysis (PTC) method for synthesis of L-proline derivatives
17:20 #37 Poster Kamil K. Kamiński Synthesis and physicochemical properties of cationic chitosan derivative for heparin complexation
17:20 #39 Poster Krzysztof Kamiński Induced Fit Homology Model of the 5-HT6 Serotonin Receptor - Application for Virtual Screening
17:20 #41 Poster Małgorzata Kapral Evaluation of transcriptional activity of genes encoding IL-6 and its receptor in colon cancer cells treated with phytic acid
17:20 #43 Poster Anna E. Kasprzycka Glycosyl O- and S- N-allyl thiocarbamates in the synthesis oligosaccharides.
17:20 #45 Poster Michał Kaza HPLC determination of cefuroxime in human plasma
17:20 #47 Poster Zygmunt Kazimierczuk Synthesis and proapoptotic properties of new casein kinase II inhibitors
17:20 #49 Poster Gabriela Kłaczkow Determination of impurities in medical products containing metformin hydrochloride
17:20 #51 Poster Szymon Kłossowski Synthesis and biological evaluation of new inhibitors of thioredoxin - thioredoxin reductase.
17:20 #53 Poster Michał Koliński Molecular dynamics of ligand binding and concurrent activation steps in opioid receptors
17:20 #55 Poster Piotr Kosson New tachykinin-opioid chimeric analogues as potential new analgesics
17:20 #57 Poster Joanna D. Kozak Functional activity of new derivatives of dextromethorphan as allosteric inhibitors of α3β4 nicotinic acetylocholine receptor.
17:20 #59 Poster Anna D. Kozioł An asymmetric synthesis of 4-aryloxyazetidin-2-ones and 3,4-benzo-2-hydroxycephams
17:20 #61 Poster Wojciech Cybulski Pharmacokinetic parameters of amoxicillin in pigs and poultry
17:20 #63 Poster Marek Kubiszewski Determination of reaction progress in synthesis of EE-3 by NMR technique
17:20 #65 Poster Rafał J. Kurczab Examination of 5-HT6 receptor affinity in the group of arylsulfonamide derivatives
17:20 #67 Poster Katarzyna Kurzepa Application of fermentation in protein hydrolysates utilisation 
17:20 #69 Poster Katarzyna Jelonek Comparison of accelerated and real-time cyclosporine A release testing from poly(L-lactide-co-trimethylene carbonate) matrices
17:20 #71 Poster Małgorzata Lisowska Kuźmicz Application of carbohydrate based chiral stationary phase for resolution of  fenoterol, clinically used chiral drug
17:20 #73 Poster Katarzyna Lubelska The possible effect of sulforaphane on the bioavailability of drugs
17:20 #75 Poster Wojciech Łuniewski Opimisation of preparation of TZ-6
17:20 #77 Poster Marcin Mączyński Electrochemical studies of Pt (II) complexes with potential bioreductive properties
17:20 #79 Poster Adam Mames  An entry to carbapenams via asymmetric Kinugasa reaction involving cyclic nitrones and terminal acetylenes
17:20 #81 Poster Magdalena Milczarek The influence of (24R)-1,24- dihydroxyvitamin D3 on the anticancer activity of 5-fluorouracil in human colon cancer model
17:20 #83 Poster Mateusz Nowak In vitro and in vivo evaluation of novel Pim kinase inhibitors with potent anticancer activity
17:20 #85 Poster Jolanta Obniska Synthesis and anticonvulsant activity of new N-Mannich bases derived from 5-cyclopropyl-5-(4-chlorophenyl)- imidazolidine-2,4-diones
17:20 #87 Poster Arkadiusz Orchel Growth of human fibroblasts in the presence of 6-hydroxyhexanoic acid
17:20 #89 Poster Gabriela Pastuch-Gawołek (5-Nitro-2-pyridyl) 1-thioglycosides: application in synthesis of analogues of glycosyltransferases natural substrates
17:20 #91 Poster Jadwiga Paszkowska Study on lipophilicity of selected uridine derivatives
17:20 #93 Poster Anita Pietraszek A novel synthesis of 19-nor analogs of vitamin D
17:20 #95 Poster Anita Płazińska Docking Study of fenoterol derivatives to the β2 adrenergic receptor. Molecular dynamic simulations for selected agonist-β2-AR complexes.
17:20 #97 Poster Mateusz Psurski Could the calorically restricted ketogenic diet be an     effective alternative or supportive therapy for breast cancer?
17:20 #99 Poster Magdalena A. Radomska Submerged cultivation of Streptomyces sp. 8812 in media containing different sources of nitrogen and carbon
17:20 #101 Poster Katarzyna Sidoryk New amino acid and peptide derivatives of 5H-indolo[2,3-b]quinoline and their biological activity.
17:20 #103 Poster Agata Siwek Synthesis and in vitro antibacterial evaluation of 1-substituted-4-ethoxycarbonylmethylthiosemicarbazides and products of their dehydrocyclization
17:20 #105 Poster Andrzej M. Składanowski New acridine-tuftsin conjugates with cytotoxic properties and increased specificity toward tumor cells
17:20 #107 Poster Sławomir Smolik The chelation ability of chosen metal ions by protective ointments containing Na2H2EDTA  and aminoacid
17:20 #109 Poster Magdalena Soluch  Straightforward Methodology for the Stereoselective Synthesis of Benzo[a]- and Indolo[2,3-a]quinolizidines
17:20 #111 Poster Marta K. Sowińska Dendrimeric peptides with  affinity to opioid receptors - complexation properties
17:20 #113 Poster Marta Świtalska Analogs of genistein and its possible anti-metastatic properties
17:20 #115 Poster Aleksandra M. Szczucińska Natural compositions with antioxidative properties
17:20 #117 Poster Katarzyna Buś-Kwaśnik LC/MS/MS determination of exemestane in human plasma
17:20 #119 Poster Kinga Trzcinska Structural characterization of PX-S
17:20 #121 Poster Jarosław Walory CHO cell line with stable expression of the HTRA1 gene as a tool for studying functional activity of 5-HT1A receptor ligands
17:20 #123 Poster Katarzyna Wiglusz Effects of nonenzymatic glycosylation and fatty acids presence on meloxicam binding to human serum albumin
17:20 #125 Poster Anna M. Wójcicka Synthesis and antitumor activity of novel 6-phenyl-2,7-naphthyridine derivatives.
17:20 #127 Poster Monika Wujec The antiviral and virucidal activity of novel 2-[(4-methyl-4H-1,2,4-triazol-3-yl) sulfanyl]acetamide derivatives
17:20 #129 Poster Paweł Zajdel Quinolinesulfonamides as potential 5-HT7 and 5-HT1A receptor ligands
17:20 #131 Poster Jadwiga R. Zawisza-Puchałka Antiproliferative activity of novel synthetic genistein glycoside derivatives
17:20 #133 Poster Marta Zezula Validation of a HPLC method for LI-S analysis
17:20 #135 Poster Tomasz Giller Iontophoretic delivery of selected antiparkinsonian agents in vitro
17:20 #137 Poster Wojciech J. Gutman New phenylpropanoic acid derivative with antidiabetic potential acting as a partial PPAR gamma agonist – preclinical studies.
17:20 #139 Poster Marcin Feder Computer aided development of dual p53-Mdm2/Mdm4 inhibitors
17:20 #141 Poster Maura D. Malińska Experimental and theoretical charge density studies on a model analogue of vitamin D
19:00 Free time
20:00 Banquet. Announcement of the Stanisław Biniecki Contest Award - Hyrny Hotel

May 11th, Tuesday

07:30 Breakfast
09:00 Session IV - Teresa M. Brodniewicz, Karol Gerla - Conference room
09:00 00:30:00 Invited oral Bogusław A. Buszewski New solutions and challenges in chromatography and related techniques. Quo vadis separation sciences?
09:30 00:30:00 Invited oral Jozef Dulak New anti-angiogenic drugs
10:00 00:20:00 Oral Katarzyna A. Koziak Endothelial P2Y receptors as novel targets for a pharmacological intervention
10:20 00:20:00 Oral Kamil K. Kamiński Cationic chitosan derivative for heparin reversal - in vitro and in vivo studies in rats
10:40 Coffee braek - Hyrny Hotel- Patio and Garden
11:10 Session V - Barbara Malawska, Józef Dulak - Conference room
11:10 00:30:00 Invited oral Grzegorz Węgrzyn The use of genistein in treatment of genetic diseases
11:40 00:20:00 Oral Jan Mazerski Microcalorimetric measurements in design of anti-tumor drugs
12:00 00:20:00 Oral Zofia Lipkowska Design of novel peptide dendrimers: antimicrobial and anticancer activity
12:20 00:20:00 Oral Mateusz Nowak Selvita: Life science solutions
12:40 00:20:00 Oral Artur Panczakiewicz A Local SCF approach to all-atom semiempirical quantum-mechanical protein modeling and ligand docking
13:00 Dinner - Hyrny Hotel - Canteen
15:00 Session VI - Marek Chmielewski, Wojciech T. Markiewicz - Conference room
15:00 00:30:00 Invited oral Aleksander P. Mazurek Molecular properties of active ingredients Impact on bioavailability The biopharmaceutics classification system
15:30 00:20:00 Oral Ryszard Ostaszewski Chemoenzymatic approach to the synthesis of bioactive tripeptide mimetics for treatment of cancer
15:50 00:20:00 Oral Mariusz Sacharczuk Comparable antinociceptive effect of biphalin in mice selected for high and low swim stress-induced analgesia after blood-brain barrier disruption caused by hyperosmolar mannitol administration
16:10 00:20:00 Oral Małgorzata Milczarek Confocal microscopy - a novel tool in drug analysis
16:30 Coffee break
17:00 Poster session II (Presentation of posters with even numbers) - Hyrny Hotel
17:00 #2 Poster Małgorzata Anyżewska Determination of total hypericins in St. John's wort and herbal medicinal products
17:00 #4 Poster Lilianna Becan Synthesis and in vitro anti-hepatitis B and C virus activity of the  new nucleobase analogues containing thiazolo[4,5-d]pyrimidine ring system
17:00 #6 Poster Krzysztof Bielawski The effect of a novel dinuclear platinum complex with berenil and 2-picoline ligands on growth and metabolism of human breast cancer cells
17:00 #8 Poster Joanna M. Biernat Problems of determination of selected Class 1 residual solvents (according to ICH*)) as process impurities of some Class 3 and 2 solvents in API by GC-HS method
17:00 #10 Poster Stanisław Boryczka New acetylenic derivatives of betulin with anticancer activity
17:00 #12 Poster Grażyna Chłoń-Rzepa Synthesis of long-chain arylpiperazine theophylline derivatives as potential 5-HT7 and 5-HT6 receptors ligands
17:00 #14 Poster Ewelina Czerniec-Michalik HPLC Methods for Stress Testing of ZL-S Drug Substances
17:00 #16 Poster Anna Długosz The role of estradiol in reducing the ethanol toxicity
17:00 #18 Poster Danuta Drozdowska Carbocyclic minor groove binders – endonuclease inhibition
17:00 #20 Poster Beata Filip-Psurska The influence of novel analogs of vitamin D3 on the antiproliferative activity of cisplatin or doxorubicin on human promyelocytic leukaemia cell line HL-60 
17:00 #22 Poster Katarzyna Gobis Synthesis and antifungal activity of novel S-esters and S,S'-diesters of N'-(2-hydroxybenzoyl) hydrazinecarbo- dithioic acids
17:00 #24 Poster Aleksandra Groman Method development and validation of an analytical procedure - control of residual 2-iodopropane in Latanoprost
17:00 #26 Poster Arkadiusz R. Gruchlik Polyunsaturated fatty acids alter expression of genes encoding antioxidant enzymes in A549 cells exposed to doxorubicin
17:00 #28 Poster Monika K. Grudzień Molecular properties impact on bioavailability of imidazole antifungal agents.
17:00 #30 Poster Jolanta Janiszewska Basic low molecular dendrimeric peptides designed for better membrane recognition
17:00 #32 Poster Katarzyna Jelonek The influence of paclitaxel on hydrolytic degradation process in matrices obtained from aliphatic polyesters and polyestercarbonates
17:00 #34 Poster Łukasz S. Kaczmarek Optimization of BR-8 synthesis
17:00 #36 Poster Agnieszka Kalicka Application of preparative HPLC for protected peptide purification
17:00 #38 Poster Krzysztof Kamiński Synthesis and anticonvulsant activity of N-substituted 8-azaspiro[4.5]decane-7,9-diones, 3-azaspiro[5.5]unde-cane-2,4-diones and 4-ethyl-4-methylpiperidine- 2,6-diones
17:00 #40 Poster Zbigniew J. Kamiński An approach towards efficient peptide synthesis in aqueous solution
17:00 #42 Poster Małgorzata Kapral The influence of inositol hexaphosphate on the expression of genes encoding matrix metalloproteinases 2 and 9 and their tissue inhibitors in human colon cancer cells
17:00 #44 Poster Anna E. Kasprzycka Regioselective protection of functional groups in the na- tural compounds.
17:00 #46 Poster Zygmunt Kazimierczuk Synthesis, antiprotozoal and antibacterial properties of new polyhalogenobenzimidazoles
17:00 #48 Poster Katarzyna Kempińska Steroid profile of Asplenium cuneifolium
17:00 #50 Poster Patrycja Kleczkowska H-Dmt-D-Lys-Phe-Phe-OH, a tetrapeptide metabolite of the opioid-neurotensin hybrid peptide PK20, expresses high antinociception
17:00 #52 Poster Beata Kolesińska Synthesis and Antimicrobial Activity of P-Tria- zinylphosphonium Salts
17:00 #54 Poster Tomasz Kosmalski Synthesis of fluorinated 2-arylo-3-aroilbenzo[b]furanes
17:00 #56 Poster Cezary J. Kowalski Differences in concentrations of tramadol and its major metabolites after per os sustained release tablet or per rectum suppository application.
17:00 #58 Poster Katarzyna A. Koziak In the quest for a new endothelium-protecting drug among escin derivatives
17:00 #60 Poster Wojciech Cybulski Tiamulin hydrogen fumarate - veterinary uses and HPLC method of determination in premixes and medicated feeds
17:00 #62 Poster Hanna Kruszewska Examination of antimicrobial activity of selected non-antibiotic products
17:00 #64 Poster Agnieszka Kuczyńska Anti-oxidativeproperties of prenylflavonoids isolated from hops (Humulus lupulus L.)
17:00 #66 Poster Rafał J. Kurczab Identification of Novel 5-HT7R Ligands via Multistep Virtual Screening of Commercially Available Compounds Databases
17:00 #68 Poster Barbara Kwiatkowska-Patzer Spinal cord peptide epitopes ameliorate immunological reaction in  experimental allergic encephalomyelitis /eae/
17:00 #70 Poster Anna A. Leśniak Assessment of analgesic potency of biphalin in a mouse model of cancer pain  
17:00 #72 Poster Hanna Liszkiewicz Synthesis and antiproliferative activity in vitro of pyridodiazepine derivatives.
17:00 #74 Poster Katarzyna Lubelska Antiprolfelative and cytotoxic effect of 5-fluorouracil and sulforaphane in Chinese hamster lung fibroblast cell line
17:00 #76 Poster Marcin Mączyński Research into transformations of 5-amino-3-methyl- 4-isoxazolecarboxylic acid hydrazide under orthoesters influence
17:00 #78 Poster Marta Majewska The development of the analytical methods for studying capsules containing Temozolomide active substance
17:00 #80 Poster Agnieszka Markowska Tripeptides with C-terminal arginine as potential inhibitors of urokinase
17:00 #82 Poster Stefan Mordalski Interaction fingerprints patterns. Binding mode analysis of mGlu2 receptor model based on docking studies
17:00 #84 Poster Jolanta Obniska Synthesis and anticonvulsant activity of new N-[4-(arylpiperazin 1-yl)]- 1,3-dioxo-1,3-dihydro-2H- isoindole- and 1,3-dioxooctahydro-2H-isoindole-2-carboxa- mides
17:00 #86 Poster Zbigniew Ochal Enzyme-catalyzed synthesis of (R)-2-(1-methyl-2-pyrro- lidine)ethanol - clemastine substrate
17:00 #88 Poster Elżbieta Pajtasz-Piasecka Effect of cyclophosphamide or 5-fluorouracil-based therapy supported by cellular vaccines on induction of immunity against transplantable MC38 colon carcinoma
17:00 #90 Poster Gabriela Pastuch-Gawołek Glycoconjugates, products of uridine derivatives phosphitylation and oxidation as glycosyltransferases potential inhibitors
17:00 #92 Poster Edyta B. Pesta-Dynda Development of RP HPLC method for the analysis of calcipotriol in cream and ointment
17:00 #94 Poster Anita Płazińska 3D-QSAR modeling of binding affinities and functional activities for the set of β2 adrenergic receptor agonists.
17:00 #96 Poster Krystyna Poręba Catalytic synthesis and antiproliferative activity in vitro of polisubstituted isoxazolopyridine derivatives.
17:00 #98 Poster Mateusz Psurski Comparison of antiproliferative activity of the natural isothiocyanates and their mercapturic derivatives.
17:00 #100 Poster Katarzyna Sidoryk The synthesis of ezetimibe with high stereochemical purity
17:00 #102 Poster Sylwia K. Sitek Comparison of UPLC and HPLC using Flutamide as an example
17:00 #104 Poster Agata Siwek Synthesis, antimicrobial, and pharmacological properties of thiadiazole derivatives
17:00 #106 Poster Sławomir Smolik Microsatellite markers analysis in the treatment and diagnosis of familial hypertrophic cardiomyopathy
17:00 #108 Poster Jolanta Solecka Novel bioactive metabolites
17:00 #110 Poster Magdalena Soluch A Novel Method for the Synthesis of Ezetimibe Precursor
17:00 #112 Poster Elżbieta U. Stolarczyk The use of the hyphenated LC-MS/MS technique for the characterisation of impurity profile of Quetiapine during drug development
17:00 #114 Poster Elżbieta Szacoń New 1-(2-pirydynyl)-6-substituted imidazo[1,2-a][1,3,5]- triazine with potential pharmacological activity.
17:00 #116 Poster Wiesław Szeja Application of 2-Nitroglycals in the Synthesis of Biologically Active Glycoconjugates
17:00 #118 Poster Katarzyna M. Targowska-Duda Molecular modeling of allosteric modulation of nicotinic acetylcholine receptor by different classes of ligands
17:00 #120 Poster Wiesława Walisiewicz-Niedbalska CLA derivatives as functional food compounds
17:00 #122 Poster Sławek Wicherkiewicz The development of the spectrofotometric and HPLC method for studying enteric coated capsules containing Duloxetine Hydrochloride active substance
17:00 #124 Poster Małgorzata Milczarek Anticancer activity of new coordinative palladium (II) complexes.
17:00 #126 Poster Joanna Zagrodzka Analytical control of synthesis and determination of BR-S by HPLC
17:00 #128 Poster Joanna Zagrodzka HPLC method as an analitycal control of synthesis and determination of TZ-S
17:00 #130 Poster Paweł Zajdel A novel handle for chemistry on solid support: the Pipecolic linker
17:00 #132 Poster Paweł Żero Cyclohexaglycine as a potential ionophore
17:00 #134 Poster Anna M. Zielińska Stability study of the coated tablets containing clopidogrel bisulfate as the active substance
17:00 #136 Poster Maria Puchalska Investigation of unknown impurity of TD-S by HPLC-MS
17:00 #138 Poster Witold S. Cieśliński The new solvates of docetaxel and C2-C3 alkyl esters of formic acid and their use for API’s preparation.
17:00 #140 Poster Witold S. Cieśliński Docetaxel trihydrate - polymorphous studies and the new useful method to obtaining one of polymorph.
18:30 Przerwa (Break)
19:00 Transportation to the Regional Inn
20:00 Picnic - Biały Potok Inn - entrance to Dolina Białego Valley, Droga do Białego 7 Str.

May 12th, Wednesday
07:30 Breakfast
09:00 Session VII - Alekasander P. Mazurek, Lech Kozerski - Conference room
09:00 00:30:00 Invited oral Waldemar Priebe Exploration of sugar-based inhibitors of glycolysis to target brain tumors
09:30 00:30:00 Invited oral Marcin Nowotny Protein crystallography as a tool in drug discovery
10:00 00:20:00 Oral Monika Lamparska-Przybysz Novel small molecule STAT3 inhibitors in cancer therapy.
10:20 00:20:00 Oral Teresa M. Brodniewicz Preclinical evaluation of new chemical entity.
10:40 Coffee break
11:10 Sesja VIII - Zofia Mazerska, Jacek Bojarski - Conference room
11:10 00:30:00 Invited oral Tomasz G. Wasiela Good Laboratory Practice as the quality system ensuring mutual acceptance of test results in the registration of pharmaceutical products.
11:40 00:20:00 Oral Kurt Kristiansen Homology modeling of G-protein coupled receptors
12:00 00:20:00 Oral Andrzej Sikorski Polymer chains as molecular dispensers. Monte Carlo simulations of simple models
12:20 00:20:00 Oral Andrzej W. Lipkowski Keratin associated proteins (KAPs) as a new biomaterials for applications in medicine and cosmetology
12:40 00:20:00 Oral Krzysztof Kurowski New phenylpropanoic acid derivative with antidiabetic potential acting as a partial PPAR gamma agonist – preclinical studies.
13:00 Dinner
15:00 Session IX - Waldemar Priebe, Zdzisław Chilmonczyk - Conference room
15:00 00:30:00 Invited oral Marek Chmielewski From unsaturated sugar α,β-lactones to β-lactams. The synthesis. Od α,β-nienasyconych laktonów cukrowych do syntezy β-laktamów.
15:30 00:20:00 Oral Zbigniew Kałuża Stereoselective synthesis of isoquinoline alkaloids with a quaternary carbon seterocenter
15:50 00:20:00 Oral Lech Kozerski Diffusion ordered  NMR spectroscopy  application  to medicines control and research  
16:10 00:20:00 Oral Zofia Mazerska Polymorphism and the level of P450 gene expression in drug metabolism
16:30 00:20:00 Oral Tomasz Kosmalski   Enantioselective reduction of α-dialkylamino ketones
16:50 Coffee break
17:20 Free time
19:00 Closure of the MKNOL Conference - Closing Banquet

May 13th, Thursday

07:30 Breakfast
09:00 Departure
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