prof Lech Kozerski

Affiliation:

Narodowy Instytut Lekow

Affiliation:

Polish Academy of Science, Institute of Organic Chemistry

Participant:

V Multidyscyplinarna Konferencja Nauki o Leku

Participant:

VI Multidyscyplinarna Konferencja Nauki o Leku

Participant:

VII Multidyscyplinarna Konferencja Nauki o Leku

Participant:

VIII Multidyscyplinarna Konferencja Nauki o Leku

Participant:

IX Multidyscyplinarna Konferencja Nauki o Leku

Publications:

1. Diffusion ordered  NMR spectroscopy  application  to medicines control and research  
2. JS-1, a novel isoquinoline alkaloid with antimicrobial activity isolated from Streptomyces sp. 8812
3. Molecular complexes of topo I and II inhibitors from camptothecin and flavonoid families with model DNA oligomers. Search for sequence specific binding. Verification of biological assays on atomic coordinates level. 
4. Molecular complexes of topo I and topo II inhibitors from camptothecin and flavonoid families with model DNA oligomers. Search from sequence specific binding. Verification of biological assay on atomic coordinates level.
5. New camptothecin derivatives alkylating DNA oligomers: the synthesis, physicochemical data and application as Topo I inhibitors
6. New generation of topoisomerase I inhibitors  from camptothecin family spontaneously covalently binding to DNA oligomers.
7. NMR INVESTIGATIONS OF HUMAN INSULIN AGGREGATION AND STRUCTURE
8. Novel medium for monomer proteins structure elucidation. Human insulin structure in water/ acetonitrile solvent. Search for nonamyloidogenic conditions
9. ¹H AND ¹³C NMR DATA FOR INDOLO[2,3-b]QUINOLINES - AMINOGLYCOSIDE HYBRIDS, A NOVEL POTENT ANTICANCER DRUG FAMILY .