prof Zdzisław Chilmonczyk

Affiliation:

Narodowy Instytut Lekow

Participant:

VI Multidyscyplinarna Konferencja Nauki o Leku

Participant:

VII Multidyscyplinarna Konferencja Nauki o Leku

Participant:

IX Multidyscyplinarna Konferencja Nauki o Leku

Publications:

1. Alkyl-nitroquipazine derivatives as serotonin transporter and 5-HT_1A receptor ligands
2. ANALYTICAL DETERMINATION OF HOMOCYSTEINE AND RELATED AMINOTHIOLS IN HUMAN PLASMA BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY WITH UV DETECTION
3. Application of amylose tris(3,5dimethylphenyl- carbamate) chiral stationary phase for the determination of paroxetine, clinically used psychotropic drug
4. Application of carbohydrate based chiral stationary phase for resolution of  fenoterol, clinically used chiral drug
5. Application of silica-bonded ovomucoin protein chiral stationary phase for the determination of paroxetine, clinically used psychotropic drug
6. CHO cell line with stable expression of the HTRA1 gene as a tool for studying functional activity of 5-HT_1A receptor ligands
7. Comparison of combined effects of 5-fluorouracil and allysin after concurrent treatment in colon and breast cancer cell lines
8. Crystal structure of β-adrenergic receptor as a new template in homology modeling of GPCR. Application to serotonin 5-HT_1A and 5-HT₇ receptors
9. Determination of the enantiomeric purity of epinephrine in pharmaceutical preparations
10. Determination of the enantiomeric purity of norepinephrine in pharmaceutical preparations
11. Direct enantiomeric resolution of tamsulosin, clinically used chiral O-phenylethanolamine derivative with α₁-blocking activity
12. ENANTIOSELECTIVITIES OF SOME 1,4-DISUBSTITUTED PIPERAZINES ON AMYLOSE CARBAMATE
13. Formation of Caco-2 monolayer - model for the prediction of intestinal drug absorption; method validation.
14. Homology modeling of G-protein coupled receptors
15. Identification of Novel 5-HT₇R Ligands via Multistep Virtual Screening of Commercially Available Compounds Databases
16. Ligand-directed receptor trafficking
17. MOBILE PHASE INFLUENCE ON CHROMATOGRAPHIC BEHAVIOUR OF SOME 1,4-DISUBSTITUTED PIPERAZINES
18. New analog of sulforaphane: 2-oxoheptyl isothiocyanate  as a compound with selective effect on the normal and colon cancer cells.
19. Proapoptotic effects of new pentabromobenzylisothioureas and CK2 inhibitor in prostate adenocarcinoma cell line
20. Serotonin transporter inhibitors inducing hypothermia at mice
21. Sulforaphane modulates MRP expression and activity in Caco-2 cells
22. SYNTHESIS AND AFFINITY FOR SEROTONIN RECEPTOR 5HT_1A AND SEROTONIN TRANSPORTER OF SOME 6-NITROQUIPAZINE ANALOGUES.
23. SYNTHESIS AND HYPOLIPIDEMIC ACTIVITY OF ASARONE ANALOGS IN MALE AND FEMALE RATS
24. Synthesis and proapoptotic properties of new casein kinase II inhibitors
25. The combined effect of 5-fluorouracil and sulforaphane in prostate cancer cell line
26. The ligand binding to the serotonin transporter