dr Joanna Wietrzyk

Affiliation:

Polish Academy of Sciences, Institute of Immunology and Experimental Therapy

Participant:

V Multidyscyplinarna Konferencja Nauki o Leku

Participant:

VI Multidyscyplinarna Konferencja Nauki o Leku

Participant:

VII Multidyscyplinarna Konferencja Nauki o Leku

Participant:

IX Multidyscyplinarna Konferencja Nauki o Leku

Publications:

1. Administration of isothiocyanate-derived mercapturic acids inhibits solid tumor growth of 4T1 murine mammary carcinoma cells in BALB/c mice
2. Analogs of genistein and its possible anti-metastatic properties
3. Anticancer activity of the conjugates:  modified fibrinogen – methotrexate.
4. Anticancer activity of vitamin D, genistein and indoloquinoline analogs
5. ANTIPROLIFERATIVE ACTIVITY IN VITRO OF DIASTEREOMERIC ANALOGUES OF VITAMIN D3 AGAINST NORMAL AND CANCER CELL LINES
6. Antitumor activity of carrier-methotrexate conjugates.
7. ANTITUMOR EFFECT OF CISPLATIN OR FLUOROURACIL IN COMBINED TREATMENT WITH (24R)-1,24-DIHYDROXYVITA- MIN D₃
8. Catalytic synthesis and antiproliferative activity in vitro of polisubstituted isoxazolopyridine derivatives.
9. CLA derivatives as functional food compounds
10. Colon cancer treatment with the use of vitamin D analogs and irinotecan 
11. COMBINATION OF: IMATINIB, PRI-2191 AND CYTOSTATICS - THE ANTIPROLIFERATIVE EFFECTS ON HL-60 LEUKEMIA CELL LINE
12. Comparison of antiproliferative activity of the natural isothiocyanates and their mercapturic derivatives.
13. CONJUGATED LINOLEIC ACIDS PREPARATIONS AS EFFECTIVE NUTRACEUTICS
14. Could the calorically restricted ketogenic diet be an     effective alternative or supportive therapy for breast cancer?
15. DISUBSTITUTED INDOLO[2,3-b]QUINOLINE DERIVATIVES. THE CYTOTOXIC ACTIVITY IN VITRO AGAINST VARIOUS HUMAN TUMOR CELL LINE.
16. Disubstituted indolo[2,3-b]quinoline derivatives - the cytotoxic activity in vitro against various human tumor cell lines.
17. FIRST ROUND STUDIES ON LEWIS LUNG CARCINOMA ACTIVITY OF THE NEW LEAD STRUCTURES IN THE ISOXAZOLE HETEROCYCLIC SYSTEM
18. GENISTEIN, ITS NEW ANALOGS AND COMPLEXES - THE ANTIPROLIFERATIVE EFFECTS ON HL-60 LEUKEMIA CELL LINE
19. Influence of Transformation of the Amino Group in Anthracyclines into -N=CH-N< or -N=CH-O- Group on Their Biological Properties
20. Interaction of endotoxin and polymyxin B in B16 mouse melanoma model of metatstasis
21. Mercapturic acids as a naturally occurring isothiocyanates prodrug form with site-directed delivery system built-in based on an oxidative environment of the tumor
22. Mono substituted 5H- and 6H-indolo[2,3-b]quinoline derivatives and their ability to overcome the barrier of drug resistance.
23. MONO SUBSTITUTED 5H-INDOLO[2,3-B]- QUINOLINE DERIVATIVES AND THEIR ABILITY TO OVERCOME THE BARRIER OF DRUG RESISTANCE.
24. Naturally occurring hydroxyalkyl isothiocyanates and isothiocyanatoalkyl benzoates - structure-activity and structure-mechanism of action relationship studies.
25. New acetylenic derivatives of betulin with anticancer activity
26. New amino acid and peptide derivatives of 5H-indolo[2,3-b]quinoline and their biological activity.
27. New amino acid derivatives of 6H-indolo[2,3-b]quinolines
28. New calcipotriol analogs, their toxicity and antitumor activity in vivo in comparison to the affinity with VDR and DBP
29. Novel bifunctional synthetic isothiocyanates with high antiproliferative activity
30. Preliminary studies on application of library of artificial receptors for differentiation of metabolites in urine of healthy and cancer mice
31. PRIMARY CYTOTOXICITY EVALUATION OF NEW HETEROCYCLIC SYSTEMS WITH PYRIDODIAZEPINE.
32. Starch derivatives as vehicles for drug delivery in anticancer therapy
33. Steroid profile of Asplenium cuneifolium
34. Synthesis and anticancer activity of acetylenic derivatives of betulin
35. Synthesis and antiproliferative activity in vitro of (4-substituted-2-butynylthio)quinolines
36. SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY IN VITRO OF NEW 2-AMINOBENZIMIDAZOLE DERIVATIVES. PART 3. REACTIONS OF 2-ARYLIDENE- AMINOBENZIMIDAZOLE WITH SELECTED 1,3-DIKETONES.
37. SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF DIACETYLENIC THIOQUINOLINES
38. Synthesis and biological activity of novel N,N-cyclic-2,4-dihydroxythiobenzamide derivatives
39. Synthesis and biological evaluation of new amino acid and dipeptide derivatives of neocryptolepine as anticancer agents. 
40. Synthesis and cytostatic activity of new 1-substituted 6H-pyrido[4,3-b]carbazole derivatives
41. SYNTHESIS AND CYTOTOXIC ACTIVITY OF 10-DEACETYL-10-PROPARGILPACLITAXEL
42. Synthesis and cytotoxic activity of new Pt (II) complexes with nitropyrazoles in aerobic and hypoxic conditions
43. Synthesis of new 5H-indolo[2,3-b]quinoline derivatives with a high selective cytotoxic activity
44. THE ANTIMETASTATIC EFFECT OF BACTERIOPHAGE T4* ADMINISTRATED IN COMBINED TREATMENT WITH SELECTED CYTOSTATICS IN MICE WITH B16 MELANOMA
45. The cytotoxic activity of glycosides of indolo[2,3-b]quinoline derivatives.
46. THE CYTOTOXIC GLYCOSIDES OF INDOLO[2,3-B]QUINOLINE DERIVATIVES. IN VITRO AND IN VIVO STUDIES
47. The influence of (24R)-1,24- dihydroxyvitamin D₃ on the anticancer activity of 5-fluorouracil in human colon cancer model
48. The influence of novel analogs of vitamin D₃ on the antiproliferative activity of cisplatin or doxorubicin on human promyelocytic leukaemia cell line HL-60 
49. The new analogs of genistein decrease mitochondrial membrane potential and activate caspase-3
50. Vitamin D analogs enhance the activity of imatinib mesylate in human non-small cell lung cancer model