Wiring of whole living bacteria with osmium-redox polymers
Lund University, Department of Analytical Chemistry, Lund SE-221 00, Sweden
Mediated electron transfer from microbial systems to electrodes represents a promising alternative to Clark electrodes. Electron mediators perform a special function in whole cell biosensors; their role is to replace the electron transfer performed by oxygen, thus preventing the process from the problem of having a low oxygen concentration . Since the first applications of osmium redox polymers for enzyme based reagentless mediated biosensing were described, polymeric mediators still attract attention due to the efficient electron shuttling properties combined with the polymeric structure promoting a stable adsorption as well as a possibility for multiple layers of both immobilised enzymes  and microbial cells  on the electrode surface.
 P. Skladal, N. O. Morozova, A. N. Reshetilov, Biosens. Bioelectron., 17 (2002) 867.
Presentation: Tutorial lecture at SMCBS'2005 Workshop, by Lo Gorton
See On-line Journal of SMCBS'2005 Workshop
Submitted: 2005-07-31 18:34 Revised: 2009-06-07 00:44