Sensitive to the adenosine 5’-triphosphate (ATP) nucleotide tailor-made molecular cavities were imprinted in a thiophene polymer network to devise and fabricate a novel chemical sensor for determination of ATP. A molecularly imprinted polymer (MIP) as a selective recognition material of the chemosensor was prepared by potentiodynamic electropolymerization. Three different functional monomers were used for complexation of one ATP molecule. The uracil substituent of bis(2,2’‑bithien‑5‑yl)methane complementary paired the adenine moiety of the target nucleotide analyte. Besides, the boronic acid of reversibly bound vicinal diol of the ribofuranose moiety. Three phosphate groups of ATP in their anionic forms, were bound with hydrogen bonds to the amide moiety of bis(2,2’‑bithien‑5‑yl)methane. In order to probe the effect of different binding motifs adopted in the present ATP recognition and to visualize the structure of the supramolecular complex formed, DFT calculations at the B3LYP/6-31G(d) level were performed. The signal transducer of this chemosensor was a 10 MHz quartz crystal resonator of an electrochemical quartz crystal microbalance (EQCM) and a Pt disk electrode for the piezoelectric microgravimetry and capacitance determination, respectively, under flow-injection analysis conditions. Properties of the MIP film were unravelled by X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared (FTIR) spectroscopy.

• Legal notice:
  

  Copyright (c) Pielaszek Research, all rights reserved.
  The above materials, including auxiliary resources, are subject to Publisher's copyright and the Author(s) intellectual rights. Without limiting Author(s) rights under respective Copyright Transfer Agreement, no part of the above documents may be reproduced without the express written permission of Pielaszek Research, the Publisher. Express permission from the Author(s) is required to use the above materials for academic purposes, such as lectures or scientific presentations.
  In every case, proper references including Author(s) name(s) and URL of this webpage: https://science24.com/paper/25140 must be provided.

1. Piezomicrogravimetric chemosensor for determination of selected alkaloids with dedicated porphyrin polymer film as recognition unit
2. Molecularly imprinted polymer (MIP) chemosensors for surface plasmon resonance (SPR) and differerntial pulse voltammetry (DPV) determination of melamine
3. Molecularly imprinted polymer based electrochemical sensors for flow injection determination of adrenaline
4. Supramolecular Solar Cells
5. Inherently chiral conducting polymer electrodes 
6. FIA detection of nicotine and cotinine using piezomicrogravimetric sensors with zinc porphyrin polymer films as their recognition elements
7. Structure-reactivity effects in electrocatalytic dioxygen reduction in aqueous solutions at electrodes coated by electrochemically synthesized molecularly imprinted polymers of a cobalt porphyrin diphenylamine derivative
8. A melamine acoustic chemosensor based on molecularly imprinted polymer film
9. An effective multipurpose building block for 3D electropolymerizations: 2,2’-bis(2,2’-bithiophene-5-yl)-3,3’-bi-1-benzothiophene
10. Bio-inspired Supramolecular Nano-Self Assemblies for Light Energy Conversion
11. Preparation and selected properties of composites of the C₆₀-Pd conducting polymer and soluble single-wall carbon nanotubes
12. Development of a histamine acoustic sensor using film of molecularly imprinted polymer prepared by electrochemical co-polymerisation of bis(bithiophene) derivatives
13. Electrochemical polymerisation and electrocatalytic properties of structured selected aminophenyl derivatives of some metalloporphyrins
14. Polymer film-coated high electron mobility transistors, based on GaN heterostructures, as sensors for some benzene derivatives
15. Mimicking Photosynthesis by Supramolecular Donor-Acceptor Nanostructures: Design to Devices
16. Mass Spectrometric and in Situ ESR Vis-NIR Spectroelectrochemical Investigations of the Mechanism of the C₆₀ Electropolymerization in the Presence of Dioxygen in Aprotic Solvents
17. Composition, structure, surface topography, and electrochemical properties of electrophoretically deposited fullerene films
18. Some electrochemical properties of laccase immobilised on the Au, IrO_x, or C₆₀-Pd polymer electrode supports
19. Formation and properties of donor-acceptor dyads of Zn porphyrins and C₆₀-imidazole adduct in the Langmuir and Langmuir-Blodgett Films
20. Electrochemical quartz crystal microbalance study of the avidin and albumin adsorption under flow injection analysis conditions
21. Electron transfer applications of nanostructured supramolecules
22. Electrochemically formed fullerene-based polymers
23. Porphyrin and Fullerene Modified Electrodes for Electrochemical Catalytic and Sensor Applications
24. Piezoelectric Microgravimetry for Determination of Some Biologically Important Compounds