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X-ray fluorescence detection of iron in diaminoacid derivatives of protoporhyrin IX.
|Monika S. Walczak 1, Krystyna Lawniczak-Jablonska 1, Andrzej Sienkiewicz 1, Iraida N. Demchenko 1, Marcin Klepka 1, Edyta Piskorska 1, Alfreda Graczyk 2, Sebastian Moss 2|
1. Polish Academy of Sciences, Institute of Physics, al. Lotników 32/46, Warszawa 02-668, Poland
The diaminoacid derivatives of protoporphyrin IX are promising in applications as photosensitizers in diagnosis and photodynamic therapy. Particularly derivatives with good water-solubility generate a lot of interests. It has been shown that due to the presence of selected amino acids residues attached to the porphyrin ring, these novel compounds penetrate more easily into tumor tissues and also clear from healthy tissues faster than others protoporphyrin-based photosensitizers. Nevertheless, the knowledge about chemistry and physical properties of these materials it still not sufficient. The one of not answered question is the role of Fe ions.
Presentation: poster at E-MRS Fall Meeting 2004, Symposium D, by Monika S. Walczak
See On-line Journal of E-MRS Fall Meeting 2004
Submitted: 2004-06-25 16:25 Revised: 2009-06-08 12:55