Nanotechnology is expected to open new avenues to fight and prevent disease using atomic scale tailoring of materials. Rapid development of bio-nanotechnology and material research lead to the new way in the combating of bacteria and to searching specific properties of nanomaterials. The study of bactericidal nanomaterials is particularly timely considering the recent increase of new resistant strains of bacteria to the most potent antibiotics.

The present work studies the bactericidal effect of silver nanoparticles in the range of 7-50 nm on Gram-negative bacteria and Gram-positive bacteria. The colloid silver nanoparticles was prepared by the modified Türkewitsch´s method. This colloid particles has the specific properties which have bactericidal effect.

Relations between bactericidal effects and physical properties of nanoparticles shall be discuss.

Acknowledgements:

This work has been supported by the Czech Ministry of Education, Youth and Sports in the framework of the Research Plan 60840770022 and by the Grant Agency of the Academy of Science of the Czech Republic, project KAN400670651 and KAN401220801

 and grant GAČR č.  202/07/0818

References:

[1] Fojtík, A., et al., Metal nanoparticles in statu nascendi (From embryonic stage of Ag nanoparticles to the metal nanoclusters), Proceedings of the International Conference NANO´06, Brno, Czech Republic

[2] Huang, L., et al., Controllable preparation of Nano-MgO and investigation of its bactericidal properties, J. Inorg. Biochem, 2005, 99(5):p. 986-93

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