The present study was undertaken on assumption that dentition status as a manifestation of lifestyle and certain hereditary predispositions may take part in modifying risk factors of CVD in youngsters from families with cardiovascular diseases and may adversely affect their state of health in future.

We enrolled 15 pairs of twins with a CVD family history. After oral health investigation the DMFT index assessing dental status was calculated. Body mass index and ratio of waist and hip, as overweight or obesity and adiposity markers, were calculated. The following laboratory tests in blood serum were done: hs-CRP, fibrinogen, lipids, apolipoproteins and glucose concentrations. Calcium, magnesium and fluoride contents were determined in enamel of teeth. Information about alcohol using, cigarette smoking, physical activity and a single 24-hours dietary recall was collected. Calculated DMFT index values were classified from 1 to 29. Rising value of DMFT was connected with worse dental health status in twins. The DMFT histogram was bimodal for values <15 and >15. The latter distribution was observed in boys only. The significant positive correlations between DMFT index values and serum LDL-C (r=0,903), Apo B (r=0,954) and glucose (r=0,975) contents were shown in boys and young men with DMFT levels over 15. The correlations between DMFT index values and intake of: amount of hard fat in diet (r=0,54) and alcohol volume (r=0,41) and cigarette smoking (r=0,39) were shown in whole group of twins. The significant negative correlations between DMFT values and ApoA1 (r=-0,39), intake of amount of soft fat (r= -0,58), dairy-products intake (r= -0,39), sweets intake and the content of ^_Mg2+ in tooth enamel (r= -0,52) were observed in this group. The significant and negative correlations were shown between content of fluorides in tooth enamel and HDL-C (r=-0,52) and ApoA1 (r=-0,63) concentrations in whole group of twins. Multivariety regression analyses revealed that DMFT values were affected by daily consumption of calories and hard fats through the influence exerted on the amount of body water and fat mass, as well as by the content of bioelements (F⁺, Mg²⁺) in enamel as determined by composition of the diet. An effect of the concentration of acute phase protein in serum was noted.

Deterioration of dentition status may coincide with elevated concentrations of risk factors of atherosclerosis. Dental care and prevention of periodontal disease should constitute an important element of primary prevention of CVD in offspring at high familial risk of CVD.

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