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Comparison of properties of porous alumina as a potential cell carrier formed by foaming and polymeric sponge methods

Zbigniew Jaegermann ,  Joanna Karaś ,  Sławomir Michałowski 

Institute of Glass and Ceramics (ISiC), Postepu 9, Warszawa 02-676, Poland

Abstract

Technology of manufacturing of porous ceramic biomaterials is an important element of elaboration of multifunctional specialised implants used by medicine. One of the roles of implants consists in bone or cartilage stimulation through the implantation of the porous grafts that contain tissue cultured in vitro. The biomaterial is a carrier of cell culture and after the implantation it helps in the tissue restoration. Porosity of the ceramic material used, as well as the shape and size of pores have to be controlled in order to obtain optimal conditions for cell culture. Porous materials properties depend to a considerable extend on the forming method applied. Therefore the present poster is a comparison of properties of porous materials formed by chemical foaming and by structural sponge methods.
Two batches of alumina porous implants were prepared: one formed by chemical foaming and the other using polyurethane sponge. Both methods were described. A comparison concerning apparent density, total porosity and compressive strength, as well as texture properties of both materials have been conducted.
The analysis of the results demonstrated that it is possible to obtain standard quality of alumina foams with a determined pore size, porosity value and adequate mechanical properties when forming the material with the use of structural sponges. All the parameters mentioned above can be controlled and steered, therefore alumina foams could be a proper carrier of implanted cells used as a stimulant agent for bone and cartilage restoration.
Acknowledgement
This work was supported by the State Committee of Scientific Research (grant No. 05/PBZ-KBN-082/2002/06)

 

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Related papers

Presentation: poster at E-MRS Fall Meeting 2003, Symposium E, by Zbigniew Jaegermann
See On-line Journal of E-MRS Fall Meeting 2003

Submitted: 2003-05-20 16:57
Revised:   2009-06-08 12:55