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Study of newly developed materials for use in endodontics regarding to its biocompatibility and biofunctionality
|Joanna Karaś 1, Andrzej Olszyna 2, Lidia Ciołek 1, Ewa Zaczyńska 3, Anna Czarny 3, Piotr Jadczyk 4, Barbara Umińska-Wasiluk 4, Jerzy Garcarek 5, Bogusława Żywicka 5
1. Institute of Ceramics and Building Materials (ICIMB), Postępu 9, Warszawa 02-676, Poland
Have been developed and manufactured biomaterials belonging to family based formulations Portland cement, as in the case of ProRoot MTA or MTA Angelus, while easy to be activated powders with suitable fluids to produce homogenous pastes.
It were developed and manufactured materials with contrast radiology, optimal consistency and good workability, adequate mechanical strength for use in endodontic treatment.
Also preferably be assessed fact that aqueous extracts of these biomaterials exhibit a pH of 10.2 and rising to 11.52 after 24 h. Developed and manufactured materials release significant quantities of calcium ions which should result in a biological environment stimulation of reparative processes pulp and repair processes in the bone tissue surrounding the root of the tooth. Based on this results may be assumed that developed materials should provide good root end filling and pulp capping.
Cytotoxicity developed cements for use in endodontics was performed by indirect contact with the monolayer cell culture L929 fibroblasts. It was no toxic effect of developed materials.
The developed biomaterials have antibacterial activity against the strains of Streptococcus mutans, Streptococcus sanguinis, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa.
Presentation: Poster at Nano and Advanced Materials Workshop and Fair, by Joanna Karaś
See On-line Journal of Nano and Advanced Materials Workshop and Fair
Submitted: 2013-08-20 15:15 Revised: 2013-09-10 12:03