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SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME 1, 5, 5-TRIMETHYL-3-CYCLOHEPTENE DERIVATIVES

Jerzy Cieplik ,  Irena Mielczarek ,  Felicja Rułko 

Wrocław Medical University, Faculty of Pharmacy, Department of Organic Chemistry, Grodzka 9, Wrocław 50-137, Poland

Abstract

During aminolysis reaction of 2, 3-epoxy-2,6,6,-trimethyl-4-cyclohepten-1-one some new hydroksyalkylo and dialkyloamino derivatives of 1, 5, 5-trimethyl-3-cycloheptene were obtained. The screening investigations of these compounds showed their various pharmacological activities. Particularly interesting are antiulcer properties of comound 3 and soporific activity of compound 5.jc2.bmp

 

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Related papers

Presentation: Poster at V Multidyscyplinarna Konferencja Nauki o Leku, by Jerzy Cieplik
See On-line Journal of V Multidyscyplinarna Konferencja Nauki o Leku

Submitted: 2006-02-08 11:35
Revised:   2009-06-07 00:44