Supplementation of area specific mineral mixture @ 50 gm per animal per day for 60 days to fluorotic buffaloes (group I) resulted in decline in plasma concentrations of Ca, Mg, Mn, Zn, Mo; while increase in Cu, Fe and F on day 60. On the other hand, supplementation of the same mineral mixture to non-fluorotic buffaloes (group II) resulted in increase in Ca, Cu, Fe, Mo, F, but decrease in Mg, Mn and Zn in blood on day 60. Day 30 values, however, showed variable trends in both group I and II.  Peripheral blood picture in both groups revealed increase in hemoglobin, hematocrit and total erythrocyte count on both day 30 and 60. Results of the present study showed favourable response of mineral mixture supplementation in fluorotic buffaloes on blood mineral profile. Moreover, improvement in blood picture, increase in milk production and clinical recovery of lameness problem further indicated beneficial effects of area specific mineral mixture supplementation in fluorotic buffaloes.

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1. Alterations in blood concentrations of macro- and micro-minerals in water buffaloes living in fluorosis endemic areas of Punjab
2. Changes in Cortisole, Oxidative Stress Indices and Serum Biochemistry in Experimental Fluoride Toxicity in Rabbits