In the last few years we have developed and used approaches that allow us to tailor the physico-chemical properties of modified electrodes at several scales. The different scales of organisation include: (a) the molecular scale for the engineering and the surface self-assembly of a redox mediator [1,2] (b) the supramolecular scale for the surface assembly of mediator, coenzyme and enzyme using non-covalent interactions [3,4] (c) the nanometer to submicrometer scale for the highly organized meso- and macroporous electrode surfaces [5,6] (d) the micrometer scale for the functionalised microelectrodes obtained by using ingredients (a)-(c). In this way, the overall bioelectrocatalytic current can be easily amplified by more than one order of magnitude, as compared to a flat electrode surface. This allows to increase significantly the detection limit and sensitivity of such a device when used as a biosensor, or the power output in the case of a biofuel cell.

[1] N. Mano, et al., J. Electroanal. Chem., 477 (1999) 79.
[2] N. Mano, et al., Electrochem .Comm., 10 (2001) 585.
[3] A. Kuhn, et al., Electroanalysis, 13 (2001) 770.
[4] A. Kuhn, et al., Biosens.&Bioelectron., 16 (2001) 653.
[5] A. Kuhn, et al., Electrochem. Comm., 5 (2003) 747.
[6] A. Kuhn, et al., J. Electroanal. Chem., 579 (2005) 181.

• Legal notice:
  

  Copyright (c) Pielaszek Research, all rights reserved.
  The above materials, including auxiliary resources, are subject to Publisher's copyright and the Author(s) intellectual rights. Without limiting Author(s) rights under respective Copyright Transfer Agreement, no part of the above documents may be reproduced without the express written permission of Pielaszek Research, the Publisher. Express permission from the Author(s) is required to use the above materials for academic purposes, such as lectures or scientific presentations.
  In every case, proper references including Author(s) name(s) and URL of this webpage: https://science24.com/paper/4415 must be provided.

1. Zmiany mikrostruktury nanokryształów chromu pod wpływem wygrzewania – badania metodą dyfrakcji promieniowania synchrotronowego
2. Electrochemical growth of alternating Metal/Polymer layers into a colloidal crystal template
3. Magnetic and crystalline microstructure of nanocrystalline metals studied by neutron and synchrotron radiation scattering