Micro and nanofabrication of molecularly imprinted polymer synthetic receptors for sensing applications

Karsten Haupt 

Compiegne University of Technology, UMR CNRS 6022, Compiegne, France

Abstract

Molecularly imprinted polymers (MIPs) are synthetic receptors produced by molding a polymer around a molecular template. MIPs may be used in the place of biomolecules as recognition elements in various applications including chemical sensors and biochips.

One of the main challenges in this respect is the interfacing of the MIP with a transducer. This is particularly true when micro or nanopatterns of MIP are to be generated, for example for multisensors or integrated microbiochips.

This talk will present different possibilities of patterning MIPs at surfaces, using techniques like micro and nanofountain pen deposition, contact and projection photolithography, soft lithography, nanomoulding, and controlled polymerisation. In addition, a number of different optical method to specifically detect the presence of the target molecule in the MIP will be described, in particular by  surface-enhanced Raman spectroscopy. A few examples of microsensors, microbiochips, and individual nanosensors based on MIPs will be discussed.

Molecularly imprinted polymers (MIPs) are synthetic receptors produced by molding a polymer around a molecular template. MIPs may be used in the place of biomolecules as recognition elements in various applications including chemical sensors and biochips. One of the main challenges in this respect is the interfacing of the MIP with a transducer. This is particularly true when micro or nanopatterns of MIP are to be generated, for example for multisensors or integrated microbiochips.

This talk will present different possibilities of patterning MIPs at surfaces, using techniques like micro and nanofountain pen deposition, contact and projection photolithography, soft lithography, nanomoulding, and controlled polymerisation. In addition, a number of different optical methods to specifically detect the presence of the target molecule in the MIP will be described, in particular by surface-enhanced Raman spectroscopy. A few examples of microsensors, microbiochips, and individual nanosensors based on MIPs will be discussed.

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Presentation: Tutorial lectore at SMCBS'2011 International Workshop, by Karsten Haupt
See On-line Journal of SMCBS'2011 International Workshop

Submitted: 2011-10-26 12:25
Revised:   2011-10-26 13:52
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