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Bioimplant effect on tendon tissue regeneration processes (clinics and experimental studies)

Lyudmila I. Donchenko 

Donetsk State Medicine University, Scientific Research Institute for Traumatology & Orthopeadics (DonIT&Or), 106, Artema St, Donetsk 83048, Ukraine


The peculiarities of degeneration and regeneration processes after autoplastics and alloplastics applications for tendon implantation for rabbits of Chinchilla breed were studied in comparison of clinical and experimental results.
The activity of studied processes was evaluated on the basis of morphological and biochemical investigations.
It was revealed on the base of experimental studies that acute at post-surgical period the degenerative- dystrophic processes are developed and moreover they were more expressed at using of the alloplastic implant as against the autoplastic one.
Since the 14-th day the regeneration processes are activated. The regeneration processes were more active for animals with autoplastic tendon in comparison with animals with alloplastics. The differences in the regeneration terms for animals with autoplastics and alloplastics are about 20-25 days.
For patients with alloplastics of tendon at the regenerate period the degenerate-dystrophic processes prevail and that in a number of cases results to complications.
Thus the obtained experimental and clinical results have the essential differences. And this fact is necessary to take into account at allotransplant applications in reconstructive surgeries.


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Related papers

Presentation: poster at E-MRS Fall Meeting 2004, Symposium B, by Lyudmila I. Donchenko
See On-line Journal of E-MRS Fall Meeting 2004

Submitted: 2004-04-29 15:34
Revised:   2009-06-08 12:55