It is well known that ethanol-induced amino acids imbalans may be an important underlain factor of alcohol cardiomyopathy. This study tested the hypothesis that ethanol-induced imbalance in the pool of the free amino acids of heart may be modified by the administration of amino acids mixture in the experimental model of alcoholism. One week alcoholization according to Majchrowizc was associated with the imbalans in the pool of free amino acids of heart. Amino acids mixture of BCAA (Leucine, Isoleucine, Valine) and Taurine (Leu:Ile:Val:Tau:1:0,25:0,25:1) in dose 500 mg/kg intragastrically, when co-administered with alcohol completely prevent development imbalance in the pool of free amino acids of heart. The results of this study suggest that imbalance in the pool of free amino acids of heart caused by alcohol consumption can be prevented by administration of amino acids mixture taurine and BCAA.

• Legal notice:
  

  Copyright (c) Pielaszek Research, all rights reserved.
  The above materials, including auxiliary resources, are subject to Publisher's copyright and the Author(s) intellectual rights. Without limiting Author(s) rights under respective Copyright Transfer Agreement, no part of the above documents may be reproduced without the express written permission of Pielaszek Research, the Publisher. Express permission from the Author(s) is required to use the above materials for academic purposes, such as lectures or scientific presentations.
  In every case, proper references including Author(s) name(s) and URL of this webpage: https://science24.com/paper/10887 must be provided.

1. Plasma homocysteine and birth defects
2. Effect of composition of BCAA and taurine on the liver amino acids pool of the rats under alcohol intoxication
3. Acute alcohol intoxication has no effect on the blood plasma and RBC levels of homocysteine