dr Gabriela Pastuch-Gawołek

Affiliation:

Silesian University of Technology, Department of Organic Chem., Bioorganic Chem. and Biotechnol.

Participant:

V Multidyscyplinarna Konferencja Nauki o Leku

Participant:

VI Multidyscyplinarna Konferencja Nauki o Leku

Participant:

VII Multidyscyplinarna Konferencja Nauki o Leku

Participant:

IX Multidyscyplinarna Konferencja Nauki o Leku

Publications:

1. 1-THIOSUGARS: SYNTHESIS AND BIOLOGICAL ACTIVITY AGAINST CSFV GLYCOPROTEINS.
2. (5-Nitro-2-pyridyl) 1-thioglycosides: application in synthesis of analogues of glycosyltransferases natural substrates
3. Application of 1-amino sugar in synthesis of glycoconjugates and determination of their biological activity toward β-1,4-galactosyltransferase
4. Application of different α-1-thioglycosides preparation methods in synthesis of 5-nitro-pyridyl 1-thioglycosides - substrates in construction of conjugates with uridine moiety
5. Evaluation of cytoxicity of glycosyl uridine derivatives
6. Fucosyl derivatives in the synthesis of uridine glycoconjugates - potential glycosyltransferase inhibitors
7. Glycoconjugates, products of uridine derivatives phosphitylation and oxidation as glycosyltransferases potential inhibitors
8. Synthesis and biological activity of synthetic β-D-glucose and β-D-galactose conjugates with various acyclic nucleosides
9. Synthesis and potential spectrum of biological activities of glycoconjugates derivatives of hydroxy-2-methylquinoline carboxylic acids
10. Synthesis of galactothiophosphoesters of uridine and preliminary tests to evaluate their activity against selected glycosyltransferases
11. Synthesis of glycosyltransferases natural substrate analogues from 1,6-anhydrosugars and acyclic uridine derivatives
12. The biological activity of sugar derivatives based on quinoline scaffold
13. The immunochemical studies of the glycinated glycoconjugates based on synthetic thioglycosides as mimic factors of bacterial endotoxins using in the polysaccharide vaccines preparation
14. Uridine derivatives of 1-thioglycosides as analogs of glycosyltransferases natural substrates
15. Uridine derivatives of heteroaryl 1-thioglycosides: synthesis and biological activity against CSFV glycoproteins