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Type of radicals formed in select siloxanurethane polymers under irradiation method of sterilization.

Izabella Legocka 1Monika Celuch 1Jarosław Sadło 1Janusz Kozakiewicz 2

1. Institute of Nuclear Chemistry and Technology (IChTJ), Dorodna 16, Warszawa 03-195, Poland
2. Industrial Chemistry Research Institute (ICRI), Rydygiera 8, Warszawa 01-793, Poland


In this preliminary study, experimental segmented poly(siloxaneurethanes) of varying length segment, designed for medical scaffolds for tissue engineering were exposed to electron beam and gamma radiation.
The films of samples packed in double sterilization pouches were irradiated with standard dose of 28 kGy used for sterilization.
The samples were irradiated using accelerator type LAE 13/9 with nominal energy of 10 MeV and 60Co gamma ray source named Minejola 1000.
None inert gas was applied. The effect of radiation on radicals formation was investigated. ESR (Electron Spin Resonance) method was used for detection present of radicals in irradiated materials. There was no signals for samples irradiated in ambient temperature, so it was necessary to carry out analogical experiment in lower temperature. Some signals with different intensivity from paramagnetic spices were observed for samples irradiated in temperature of liquid nitrogen. In order to examine kinetics of formation and decay of radicals there were carried out same experiments in various temperatures from liquid nitrogen to ambient temperature.
In the same time there were observed no differences in IR and DRS (Diffuse Reflected Spectrofotometr) spectrum of radiated and irradiated samples. It can be result of the very fast recombination proces of new-created radicals. After modification selected poly(siloxaneurethanes) with scavengers of radicals there was observed decrease intensivity of signals in ESR spectrum.


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Related papers

Presentation: poster at E-MRS Fall Meeting 2003, Symposium E, by Izabella Legocka
See On-line Journal of E-MRS Fall Meeting 2003

Submitted: 2003-05-27 12:33
Revised:   2009-06-08 12:55