Synthesis of 2-phenylimidazole derivatives and their coordination properties have been studied. 2-Phenylimidazole-4-carbaldehyde has been chosen as starting material in this work. Base catalyzed Knoevenagel condensation [1] of 2-phenylimidazole-4-carbaldehyde with various active methylene group compounds has been used to produce a series of ten 4-substituted 2-phenylimidazole derivatives. Identity and purity of all products has been confirmed by ¹H NMR and ¹³C NMR spectroscopy, elemental analysis and by GC/MS. Coordination properties of all prepared substances have been tested. The formation of Cu(II) complexes in solution has been studied by UV/VIS spectroscopy. The results have been compared with 2-phenylimidazole and 2-phenylimidazole- 4-carbaldehyde.

[1] H. McNab, C. Thornley, J. Chem. Soc. Perkin Trans. 1 1997, 2203.

The authors are indebted to the Ministry of Education, Youth and Sports of the Czech Republic for financial support (Research project MSM 0021627501).

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