Now medical treatment for bone defects involves replacement of lost bone with an artificial material. Tissue engineering offers the perspective to regrow missing bone by culturing new cells on synthetic scaffolds.
The first step of our investigations is aimed to choose potential bone scaffold material, to develop models of nanocarbon molecule behaviour (fullerenes, multi-walled carbon nanotubes MWCNT) in environment of simulated body fluid (SBF) [1]. Main process was studied: nanocarbon molecules participation in the formation of hydroxyapatite crystals which are formed during bone mineralization. We found that modified C60 molecule and MWCNT scaffolds, having bio- positive or negative charge in nanofluids, provide the best environment for hydroxyapatite crystal growth in SBF with chemically synthesised hydroxyapatite Ca10(PO4)6(OH)N nanopowder. The perspective of the investigation area have been confirmed by pioneering results at University of California, Riverside that demonstrates the topography single bone forming cell on MWCNT [2].

References:
1. O. Lysko et al. Bulletin of the University of Kyiv. Series: Physics and Mathematics, 2002, 3, 323
2. Laura Zanello et al. Nano Lett. 2006, 6, 562.

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