NMR Studies of Hydrogen Bond Structure and Dynamics: from Crystals, Liquids, Mesoporous Media to Enzymes

Hans H. Limbach 

Free University Berlin (FUB), Takustr. 3, Berlin 14195, Germany

Abstract
http://userpage.chemie.fu-berlin.de/~limbach

Recent applications of low-temperature liquid and solid state NMR spectroscopy in the study of H-transfer and H-bonding are described. "H-transfer NMR" focuses on the kinetics of H and D transfers in weak hydrogen bonds [1], "H-bond NMR" on strong hydrogen bonds [2]. Using low-temperature NMR methods acid-base interactions in polar solvents can be studied. Dipolar solid state NMR of selected systems provides a link between crystallography and the world of NMR parameters. Applications to mesoporous silica host-guest systems [3], transition metal complexes and nanoparticles [4, 5], poly-L-lysine, as well as enzyme models and enzymes are presented.

I thank for their contribution to this work: G. Buntkowsky, Jena, G. S. Denisov, N. S. Golubev, St. Petersburg, I. Shenderovich, P. Tolstoy, Berlin, B. Chaudret, Toulouse, J. Elguero, R. Claramunt, Madrid, D. Silverman, Gainesville, M. Toney, Davis.

[1] H. H. Limbach, in Enz. of NMR: Suppl. Vol. 9, Wiley 2002, pp. 520. Dynamics of H-Transfer in Liquids and Solids.

[2] H. H. Limbach, G. S. Denisov, N. S. Golubev, in Isotope Effects In Chemistry and Biology, A. Kohen, H. H. Limbach, Eds.; 2005; Chapter 7, pp 193. H-Bond Isotope Effects Studied by NMR.

[3] I. G. Shenderovich, G. Buntkowsky, H. H. Limbach et al., J. Phys. Chem. B. 2003, 107, 11924: Pyridine-15N - a Mobile NMR Sensor for Surface Acidity and Surface Defects of Mesoporous Silica.

[4] J. Matthes, G. Buntkowsky, B. Chaudret, H. H. Limbach et al., J. Am. Chem. Soc. 2004, 126, 8366: Bridging the Gap between Hom. and Het. Catalysis: o/p-H2 Conversion, H-Isotope Scrambling and Hydrogenation of Olefins.

[5] T. Pery, K. Pelzer, G. Buntkowsky, K. Philippot, H. H. Limbach, B. Chaudret., Chem. Phys. Chem. 2005, 6, 605: Direct NMR Evidence for the Presence of Mobile Surface Hydrides on Ru-Nanoparticles.

Legal notice
  • Legal notice:

    Copyright (c) Pielaszek Research, all rights reserved.
    The above materials, including auxiliary resources, are subject to Publisher's copyright and the Author(s) intellectual rights. Without limiting Author(s) rights under respective Copyright Transfer Agreement, no part of the above documents may be reproduced without the express written permission of Pielaszek Research, the Publisher. Express permission from the Author(s) is required to use the above materials for academic purposes, such as lectures or scientific presentations.
    In every case, proper references including Author(s) name(s) and URL of this webpage: http://science24.com/paper/7425 must be provided.

 

Presentation: invited lecture at 18th Conference on Physical Organic Chemistry, Plenary session, by Hans H. Limbach
See On-line Journal of 18th Conference on Physical Organic Chemistry

Submitted: 2006-04-25 19:05
Revised:   2009-06-07 00:44
Google
 
Web science24.com
© 1998-2021 pielaszek research, all rights reserved Powered by the Conference Engine