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Preparation of antimicrobial nanoparticles containing chitosan

Kinga Brzoza-Malczewska ,  Magdalena Kucharska ,  Maria Wiśniewska-Wrona 

Instytut Biopolimerów i Włókien Chemicznych w Łodzi, ul. M. Skłodowskiej-Curie 19/27, Łódź 90-570, Poland

Abstract

In recent years, the number of diseases caused by microbiological and nosocomial infection increased, which led to intensive research on new materials for medical and hygiene products.The fibrous materials used so far for medical and hygienic applications, which gained antimicrobial properties, were usually obtained using a treatment with salts and/or nanoparticles of silver. Currently it is common to depart from the use of silver in dressings materials, and therefore and interest in research and technology development based on the use of alternative renewable materials has increased.

In this work modern fibrous cellulose products modicied by chitosan nanoparticles were developed. For the modification of cellulose fibers a useful form of chitosan - microcrystalline chitosan (MCCh) and a complex od chitosan/alginate of nanometric dimension were developed. A method of applying chitosan nanoparticles on fibrous cellulose products was elaborated. The modified products obtained were subjected to the assesment of their antimicrobial activity as well as physico-mechanical and sorption properties.

Tests were carried out within the project No. NCBiR/ERA-NET-MATERA/01/2011 "Advanced Cellulose Materials - AdvanCellMat"

 

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Related papers

Presentation: Poster at Nano PL 2014, Symposium B, by Kinga Brzoza-Malczewska
See On-line Journal of Nano PL 2014

Submitted: 2014-08-29 12:20
Revised:   2014-08-29 12:38