Analysis of the early stages of crystallization is of crucial importance to understand nucleation and growth processes. Several methods will be presented, which are able to deliver information in the size range between atoms and nanoparticles in solution. A particularly powerful method is Analytical Ultracentrifugation. It will be shown that species from prenucleation clusters to nanoparticles can be detected in solution with angström size resolution and high statistical significance since every particle is detected. An ultracentrifugation technique will be shown, which allows to perform nucleation experiments directly in the spinning rotor. Application of a newly developed UV/Vis detector allows to simultaneously obtain the UV/Vis spectra of all detected species which is very advantageous for metal and semiconductor nanoparticles. Other techniques like Taylor diffusion or mass spectrometry will also be discussed regarding their application to analyse early stages of crystallization processes.

• Legal notice:
  

  Copyright (c) Pielaszek Research, all rights reserved.
  The above materials, including auxiliary resources, are subject to Publisher's copyright and the Author(s) intellectual rights. Without limiting Author(s) rights under respective Copyright Transfer Agreement, no part of the above documents may be reproduced without the express written permission of Pielaszek Research, the Publisher. Express permission from the Author(s) is required to use the above materials for academic purposes, such as lectures or scientific presentations.
  In every case, proper references including Author(s) name(s) and URL of this webpage: https://science24.com/paper/28731 must be provided.

1. Non-Classical Nucleation of Calcium Sulfate: A Novel View on the Origin of Scale Formation