Fluoride in high concentration can cause bad effects on different parts of human body for example dental and skeletal. According to the WHO guideline, fluoride concentration in drinking water should be limited in 1.5 mg/l. Therefore, finding a suitable method to remove the excess amount of fluoride is very necessary. Today, the economical and environmental aspects to choose the effective technology for water treatment is very important and then the use of membrane technology get improved. The efficiency of nanofiltaration membrane (NF33, 1812-50, FILMTEC) to remove fluoride from water was investigated. The effects of some chemical (initial amount of fluoride, sulfate and electrical conductivity (EC) and the effect of associated cation with fluoride ion) and physical (flow rate) parameters to remove fluoride are studied. Obtain results from this study show that in all experiment fluoride concentration in permeate water were in standard range. In addition the fluoride removal efficiency decreased with increasing in initial amounts of fluoride, sulfate and EC in feed water and increasing in flow rate. Moreover, this efficiency for CaF₂ was higher than NaF.

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