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Electrochemical Sample Pretreatment and Detection Techniques for Lab-on-a-Chip Applications
|Leif Nyholm 1, Gustav Liljegren 1, Oliver Klett 2|
1. Uppsala University, Department of Analytical Chemistry, P.O. Box 599, Uppsala, Sweden
As a result of the rapid development within the field of lab-on-a-chip systems, there is currently a growing interest in miniaturised electrochemical devices. This can be explained by the fact that electrochemical devices can be readily miniaturised and that the required electrodes can be manufactured with standard microfabrication techniques. Electrochemically controlled solid-phase microextraction, employing electronically conducting polymers, is a new promising sample pretreatment technique [1-3]. As the extraction and desorption of analytes is controlled merely by the potential of the conducting polymer, this technique is highly suitable for inclusion in miniaturised chip-based systems. By use of electrochemical detection in capillary electrophoresis, employing e.g. arrays of microfabricated electrodes [4, 5], both efficient chip-based separations and low detection limits can be obtained even for complex samples.
Presentation: Keynote lecture at SMCBS 2003 Workshop, by Leif Nyholm
See On-line Journal of SMCBS 2003 Workshop
Submitted: 2003-09-15 15:09 Revised: 2009-06-08 12:55