Organization and Dynamics within Supported Interfaces:  Implications for the Creation of Biomimetic Structures

Stephan Baumler Benjamin P. Oberts Monika J. Dominska Gary J. Blanchard 1

1. Michigan State University, Department of Chemistry (MSU), East Lansing, MI 48824, United States

Abstract

The creation of biomimetic support structures capable of supporting transmembrane proteins in their active form has proven to be a challenging task.  The inherent structural and compositional complexity of the plasma membrane makes the task of creating a synthetic equivalent difficult.  Issues such as the composition and morphology of supporting underlayers and the attachment of a biomimetic layer to an interface are central to success.  Much of the recent focus of our group has been on methods for binding lipid adlayers to interfaces while retaining fluidity.  A substantial concern for such systems is the extent to which the interfacial structure is influenced by the interface binding chemistry and its immediate environment.  An overview of recent advances in this area will be presented.

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Presentation: Tutorial lectore at SMCBS'2011 International Workshop, by Gary J. Blanchard
See On-line Journal of SMCBS'2011 International Workshop

Submitted: 2011-08-30 14:12
Revised:   2011-08-30 14:12
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