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Chitosan-Multiwall Carbon Nanotubes For Applications in Tissue Engineering

Imelda O. Armendariz 1Perla E. Garcia-Casillas 1Alberto M. Villafañe 2Carlos A. Martínez 1

1. Universidad Autonoma de Ciudad Juarez, Ave. del Charro 450 Norte, Juarez 32360, Mexico
2. Centro de Investigaciones en Materiales Avanzados, SEP-Conacyt (CIMAV), Miguel de Cervantes No. 120, complejo industrial Chihuahua, Chiuahua 31109, Mexico

Abstract

In the search for ideal materials for tissue engineering where the properties of scaffolds are dictated concurrently by different factors such as degradation rate, mechanical properties, site of implant, kinetics of cell growth, etc. it’s common to blend or make composite of two or more materials in order to modulate its properties. In this work the preparation of Chitosan-MWCNT Scaffold by thermal induced phase separation technique (TIPS) is presented. The effects of the different parameters as solvent type, polymer concentration, and quenching temperature for the production of the scaffolds were studied. Biodegradable materials with 3D interconnected porous with pore size between 100-300 µm were obtained. The incorporation of the MWCNT improved the mechanical properties of the scaffolds. The bioactivity of the materials was tested in vitro using a simulated body fluid (SBF). The Scaffolds were soaked in this solution for different period of time showing the formation of biological apatite alike that shows its potential in tissue engineering.

 

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Related papers

Presentation: Poster at E-MRS Fall Meeting 2008, Symposium L, by Carlos A. Martínez
See On-line Journal of E-MRS Fall Meeting 2008

Submitted: 2008-05-19 20:13
Revised:   2009-06-07 00:48