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dr Joanna Wietrzyk

e-mail:
phone: +48-71-3371172
fax: +48-71-3371382
web:
interest(s):

Affiliation:


Polish Academy of Sciences, Institute of Immunology and Experimental Therapy

address: Rudolfa Weigla 12, Wrocław, 53-114, Poland
phone: +48-071-3709942
fax: +48-071-3709942
web: http://www.iitd.pan.wroc.pl

Participant:


V Multidyscyplinarna Konferencja Nauki o Leku

began: 2006-05-15
ended: 2006-05-17
Presented:

V Multidyscyplinarna Konferencja Nauki o Leku

ANTIPROLIFERATIVE ACTIVITY IN VITRO OF DIASTEREOMERIC ANALOGUES OF VITAMIN D3 AGAINST NORMAL AND CANCER CELL LINES

Participant:


VI Multidyscyplinarna Konferencja Nauki o Leku

began: 2008-05-25
ended: 2008-05-29
Presented:

VI Multidyscyplinarna Konferencja Nauki o Leku

New amino acid derivatives of 6H-indolo[2,3-b]quinolines

Participant:


VII Multidyscyplinarna Konferencja Nauki o Leku

began: 2010-05-09
ended: 2010-05-13
Presented:

Participant:


IX Multidyscyplinarna Konferencja Nauki o Leku

began: 2014-05-11
ended: 2014-05-15
Presented:

IX Multidyscyplinarna Konferencja Nauki o Leku

Anticancer activity of vitamin D, genistein and indoloquinoline analogs

Publications:


  1. Administration of isothiocyanate-derived mercapturic acids inhibits solid tumor growth of 4T1 murine mammary carcinoma cells in BALB/c mice
  2. Analogs of genistein and its possible anti-metastatic properties
  3. Anticancer activity of the conjugates:  modified fibrinogen – methotrexate.
  4. Anticancer activity of vitamin D, genistein and indoloquinoline analogs
  5. ANTIPROLIFERATIVE ACTIVITY IN VITRO OF DIASTEREOMERIC ANALOGUES OF VITAMIN D3 AGAINST NORMAL AND CANCER CELL LINES
  6. Antitumor activity of carrier-methotrexate conjugates.
  7. ANTITUMOR EFFECT OF CISPLATIN OR FLUOROURACIL IN COMBINED TREATMENT WITH (24R)-1,24-DIHYDROXYVITA- MIN D3
  8. Catalytic synthesis and antiproliferative activity in vitro of polisubstituted isoxazolopyridine derivatives.
  9. CLA derivatives as functional food compounds
  10. Colon cancer treatment with the use of vitamin D analogs and irinotecan 
  11. COMBINATION OF: IMATINIB, PRI-2191 AND CYTOSTATICS - THE ANTIPROLIFERATIVE EFFECTS ON HL-60 LEUKEMIA CELL LINE
  12. Comparison of antiproliferative activity of the natural isothiocyanates and their mercapturic derivatives.
  13. CONJUGATED LINOLEIC ACIDS PREPARATIONS AS EFFECTIVE NUTRACEUTICS
  14. Could the calorically restricted ketogenic diet be an     effective alternative or supportive therapy for breast cancer?
  15. DISUBSTITUTED INDOLO[2,3-b]QUINOLINE DERIVATIVES. THE CYTOTOXIC ACTIVITY IN VITRO AGAINST VARIOUS HUMAN TUMOR CELL LINE.
  16. Disubstituted indolo[2,3-b]quinoline derivatives - the cytotoxic activity in vitro against various human tumor cell lines.
  17. FIRST ROUND STUDIES ON LEWIS LUNG CARCINOMA ACTIVITY OF THE NEW LEAD STRUCTURES IN THE ISOXAZOLE HETEROCYCLIC SYSTEM
  18. GENISTEIN, ITS NEW ANALOGS AND COMPLEXES - THE ANTIPROLIFERATIVE EFFECTS ON HL-60 LEUKEMIA CELL LINE
  19. Influence of Transformation of the Amino Group in Anthracyclines into -N=CH-N< or -N=CH-O- Group on Their Biological Properties
  20. Interaction of endotoxin and polymyxin B in B16 mouse melanoma model of metatstasis
  21. Mercapturic acids as a naturally occurring isothiocyanates prodrug form with site-directed delivery system built-in based on an oxidative environment of the tumor
  22. Mono substituted 5H- and 6H-indolo[2,3-b]quinoline derivatives and their ability to overcome the barrier of drug resistance.
  23. MONO SUBSTITUTED 5H-INDOLO[2,3-B]- QUINOLINE DERIVATIVES AND THEIR ABILITY TO OVERCOME THE BARRIER OF DRUG RESISTANCE.
  24. Naturally occurring hydroxyalkyl isothiocyanates and isothiocyanatoalkyl benzoates - structure-activity and structure-mechanism of action relationship studies.
  25. New acetylenic derivatives of betulin with anticancer activity
  26. New amino acid and peptide derivatives of 5H-indolo[2,3-b]quinoline and their biological activity.
  27. New amino acid derivatives of 6H-indolo[2,3-b]quinolines
  28. New calcipotriol analogs, their toxicity and antitumor activity in vivo in comparison to the affinity with VDR and DBP
  29. Novel bifunctional synthetic isothiocyanates with high antiproliferative activity
  30. Preliminary studies on application of library of artificial receptors for differentiation of metabolites in urine of healthy and cancer mice
  31. PRIMARY CYTOTOXICITY EVALUATION OF NEW HETEROCYCLIC SYSTEMS WITH PYRIDODIAZEPINE.
  32. Starch derivatives as vehicles for drug delivery in anticancer therapy
  33. Steroid profile of Asplenium cuneifolium
  34. Synthesis and anticancer activity of acetylenic derivatives of betulin
  35. Synthesis and antiproliferative activity in vitro of (4-substituted-2-butynylthio)quinolines
  36. SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY IN VITRO OF NEW 2-AMINOBENZIMIDAZOLE DERIVATIVES. PART 3. REACTIONS OF 2-ARYLIDENE- AMINOBENZIMIDAZOLE WITH SELECTED 1,3-DIKETONES.
  37. SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF DIACETYLENIC THIOQUINOLINES
  38. Synthesis and biological activity of novel N,N-cyclic-2,4-dihydroxythiobenzamide derivatives
  39. Synthesis and biological evaluation of new amino acid and dipeptide derivatives of neocryptolepine as anticancer agents. 
  40. Synthesis and cytostatic activity of new 1-substituted 6H-pyrido[4,3-b]carbazole derivatives
  41. SYNTHESIS AND CYTOTOXIC ACTIVITY OF 10-DEACETYL-10-PROPARGILPACLITAXEL
  42. Synthesis and cytotoxic activity of new Pt (II) complexes with nitropyrazoles in aerobic and hypoxic conditions
  43. Synthesis of new 5H-indolo[2,3-b]quinoline derivatives with a high selective cytotoxic activity
  44. THE ANTIMETASTATIC EFFECT OF BACTERIOPHAGE T4* ADMINISTRATED IN COMBINED TREATMENT WITH SELECTED CYTOSTATICS IN MICE WITH B16 MELANOMA
  45. The cytotoxic activity of glycosides of indolo[2,3-b]quinoline derivatives.
  46. THE CYTOTOXIC GLYCOSIDES OF INDOLO[2,3-B]QUINOLINE DERIVATIVES. IN VITRO AND IN VIVO STUDIES
  47. The influence of (24R)-1,24- dihydroxyvitamin D3 on the anticancer activity of 5-fluorouracil in human colon cancer model
  48. The influence of novel analogs of vitamin D3 on the antiproliferative activity of cisplatin or doxorubicin on human promyelocytic leukaemia cell line HL-60 
  49. The new analogs of genistein decrease mitochondrial membrane potential and activate caspase-3
  50. Vitamin D analogs enhance the activity of imatinib mesylate in human non-small cell lung cancer model



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