The N-alkyl derivatives of 7-chloro-5- chlopropyl-9-methyl-5, 10-dihydro-4, 5,6,10-tetraaza-dibenzo [a, d] cyclohepten-11-one have been synthesized and characterized by X-ray diffraction analysis. The azepine ring in all the structures adopts a boat conformation and the overall molecular shape of the fused ring is that of a butterfly. The cyclopropyl ring in all the structures is orthogonal to the fused ring system. The structures exhibit intermolecular hydrogen bonds of the type C-H…O, C-H…Cl. and C-H…Br. The starting material “7-chloro-5-chclopropyl-9-methyl-5, 10-dihydro-4, 5,6,10-tetraaza-dibenzo [a, d] cyclohepten-11-one“ is an intermediate of a potent anti-HIV drug Nevirapine. Implications of the derivatives of the intermediate and their biological activities of the molecules with the structure-activity relationships are under progress.

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1. Synthesis and Anti-microbial Activities of Thiazolidin-4-one Derivatives