Mechanistic Aspects and Synthetic Application of Carbon-Carbon and Carbon Heteroatom Bonds Formation in Substitution and Addition Reactions Catalyzed by Transition Metal Complexes

Irina P. Beletskaya ,  Valentin P. Ananikov 

Chemistry Department, Moscow State University, Leninskie Gory, 1-3, Moscow 119992, Russian Federation

Abstract

1. Pd-catalyzed reaction of carbon-carbon (cross-coupling reactions, Heck reaction, carbonylative cross coupling) and carbon-heteroatom (C-S, C-Se, C-P, C-N) bonds formation will be shortly considered from the viewpoint of generality and differences in their mechanisms.

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2. The addition of element-element and element-hydrogen bonds to triple bond of alkynes (terminal and internal) will be illustrated by the examples of S-S, Se-Se, P-P and S-H, Se-H, P-H bonds addition and considered from the viewpoints of their mechanism, regio- and stereoselectivity.

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The influence of the nature of transition metal (Pd, Pt, Ni) on the product formation, the effect of using heterogeneous viz homogeneous catalysts will be considered from the viewpoints of intermediates formed and the size of nanoparticles involved.

3. Several examples of Pd- and Ni-catalyzed addition reactions of E-H bonds to the double bond of nonactivated alkenes will be also discussed.

 

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Presentation: plenary lecture at 18th Conference on Physical Organic Chemistry, Plenary session, by Irina P. Beletskaya
See On-line Journal of 18th Conference on Physical Organic Chemistry

Submitted: 2006-05-12 16:26
Revised:   2009-06-07 00:44