Making Crystals from Crystals: a Green Route to Crystal Engineering and Polymorphism
University of Bologna, Dipartimento di Chimica "G. Ciamician" (UNIBO), via Selmi 2, Bologna 40126, Italy
Supramolecular reactions between crystalline materials or reactions between a crystalline material and a vapour can be used to generate new crystalline substances as well as crystal polymorphs, solvates, salts and co-crystals. These solvent-free processes can be exploited to prepare both hydrogen bonded co-crystals and coordination networks by non-solution solvent-free methods. Solid-vapour reactions do not differ from solid-gas uptake/release processes, and can also be used to prepare polymorphs and solvates. It is argued that solvent-less reactions involving molecular crystals represent a green route to supramolecular solid state chemistry and a viable alternative to solution methods for a thorough mapping of the "crystal space" (crystal reactivity, stability, vapour uptake/release, behaviour under mechanical stress, etc.). Examples will be provided in a broad range from organic molecular crystals, to coordination networks and salts.
Presentation: plenary lecture at 18th Conference on Physical Organic Chemistry, Plenary session, by Dario Braga
See On-line Journal of 18th Conference on Physical Organic Chemistry
Submitted: 2006-04-21 11:39 Revised: 2009-06-07 00:44