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New array detector for protein crystallography at the Argonne National Laboratory

Istvan Naday 1Timothy Madden 1Gerold Rosenbaum 2

1. Argonne National Laboratory (ANL), 9700 South Cass Avenue, Argonne, IL 60439, United States
2. University of Georgia, Athens, GA, United States

Abstract

A new advanced CCD/fiberoptic array detector is being developed for the Structural Biology Beamlines at the Advanced Photon Source. The new detector, called Clematis-1330, uses a novel geometrical arrangement of the fiberoptic tapers resulting in a circular like imaging area with an equivalent diameter of 412 mm. Additional features such as selectable readout speeds, software controlled binning, gain and offset adjustments of the individual modules and self testing modes make this new generation fiberoptic taper / CCD array detector a flexible and reliable device for macro-molecular beamlines. The very large active area (1330 cm2) with the new geometry combined with high spatial resolution provides for a substantial increase in solid angle coverage significantly improving anomalous data collection for phasing at low energies, increasing the number of resolved orders per frame for large macromolecular assemblies, reducing the dose on the sample, i.e radiation damage, for the same resolution and completeness of data, and giving more leeway in detector distance for minimizing background. The added novel gain control feature makes this detector particularly suited for acquisition of very-high resolution data.. Independent read-out speed control allows balancing the opposing quests for low read-noise and short read-out times. An overview of the hardware and software design and specifications, as well as a comparison of its performance parameters with existing detectors will be given.

 

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Related papers

Presentation: invited oral at E-MRS Fall Meeting 2004, Symposium D, by Istvan Naday
See On-line Journal of E-MRS Fall Meeting 2004

Submitted: 2004-06-22 20:52
Revised:   2009-06-08 12:55