Novel Nanocomposite Biosensor for Potassium Ion Sweat Test

Pelagia I. Gouma ,  Ruipeng Xue 

State University of New York (SUNYSB), Department of Material Science and Engineering, Stony Brook 11794-2275, United States


Potassium ions (K+) level in the human body is critical for the electrolyte balance of the body and the nerves and muscles functions. So it is very important to accurately and rapidly determine potassium concentrations in human fluids in clinical fields.  This paper describes a novel concept for a potassium ion biosensor that accurately, rapidly, and efficiently monitors the presence and records the concentration of potassium ions with high specificity, not only in serum and urine, but also in the sweat or even eye fluid. This specific biosensor design utilizes a nanomanufacturing technique, i.e. electrospinning, to produce advanced nano-bio-composites that specifically trace even minute quantities of potassium ions through the use of selective bio-receptors (ionophores) attached to high surface area nanofibers. Electroactive polymers are then employed as transducers to produce an electronic (rather than ionic) output that changes instantly with the change in K+ concentration. A convenient, non-invasive, maintenance-free “Band-aid” type configuration of skin patch is demonstrated in this paper.

Legal notice
  • Legal notice:

    Copyright (c) Pielaszek Research, all rights reserved.
    The above materials, including auxiliary resources, are subject to Publisher's copyright and the Author(s) intellectual rights. Without limiting Author(s) rights under respective Copyright Transfer Agreement, no part of the above documents may be reproduced without the express written permission of Pielaszek Research, the Publisher. Express permission from the Author(s) is required to use the above materials for academic purposes, such as lectures or scientific presentations.
    In every case, proper references including Author(s) name(s) and URL of this webpage: must be provided.


Related papers
  1. Effects of reverse polarity on electrospun fiber nanocomposites
  2. Selective Chemosensor Breathanalyzers – Non-Invasive Disease Diagnostic Tools
  3. Growth Mechanism of 3D CuO Nanogrids

Presentation: Oral at E-MRS Fall Meeting 2009, Symposium F, by Ruipeng Xue
See On-line Journal of E-MRS Fall Meeting 2009

Submitted: 2009-05-11 22:19
Revised:   2009-06-07 00:48
© 1998-2022 pielaszek research, all rights reserved Powered by the Conference Engine