Over the years, several methods have been developed to coat solid surfaces for biotechnological applications. Success has primarily been achieved by using wet chemical methods employing solvents, or strong acid / base media, some of which are becoming increasingly unacceptable due to environmental and safety concerns.  An alternative approach is to employ non-isothermal plasmachemical processing.  This technology offers many potential benefits including low energy consumption, absence of solvents, minimal waste, rapid treatment times, ambient temperatures, applicability to a whole host of different substrate materials, and control of surface functionality.  Specific examples will be given including high throughput and low-cost technological solutions for preparing re-writable DNA microarrays, protein chips, antibacterial surfaces, thermo-responsive coatings for tissue engineering, and substrates for rapid cell growth.

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