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Absorbable surgical sutures on the base of cellulose phosphate

Nikolay Yurkshtovich ,  Natalija Golub ,  Fedor Kaputski 

Research Institute of physical-chemical problems (FHP), Leningradskaja 14, Minsk 220050, Belarus

Abstract

The relevant problem at building surgical stuffs is the development of the degradable surgical sutures with adjustable terms of the resorption. Series of valuable properties of the cellulose phosphate: biocompatibility, degradation in tissues of an alive organism, and also variety of the physical forms, - enable the applying them as a surgical suture material.
The influence of the conditions of the phosphorylation in the system on the contents of the phosphate groups, explosive strain in a dry condition and in a knot, the lose of strength in vitro and in vivo of the viscose and the cotton fibers were studied. The studies in vivo have shown, that the explosive strain of a suture material on the basis of the cellulose phosphate with metabolic capacitance of 0,25 - 0,5 mmol/g is conserved practically invariable for 30 day. At 60-th day after an implantation the biodegradation of fibers is observed. The complete resorption takes place at 180-th day.

 

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Related papers

Presentation: poster at E-MRS Fall Meeting 2004, Symposium B, by Nikolay Yurkshtovich
See On-line Journal of E-MRS Fall Meeting 2004

Submitted: 2004-03-22 12:47
Revised:   2009-06-08 12:55